SCHEMBL219454

SCHEMBL219454

c1cnc2conc2c1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8194 0.73 ALDH1A1 (0.67)
SCHEMBL30099834 0.73 ALDH1A1 (0.67)
SCHEMBL3417508 0.70 ALDH1A1 (0.36)
SCHEMBL28519048 0.70 ALDH1A1 (0.63)
SCHEMBL29592061 0.70 ALDH1A1 (0.63)
Water SCHEMBL28824188 0.70 ALDH1A1 (0.63)
Hydrochloric Acid SCHEMBL3439030 0.70 ALDH1A1 (0.63)
Hydrochloric Acid SCHEMBL3710107 0.70 ALDH1A1 (0.63)
Hydrochloric Acid SCHEMBL3704751 0.70 ALDH1A1 (0.63)
Hydrogen Sulfide SCHEMBL29184282 0.70 ALDH1A1 (0.63)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 453 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119661537-A Nucleoside compound, preparation method thereof, composition thereof and application of nucleoside compound in medicine 中国科学院上海药物研究所 2025-03-21 CN claimed
US-20240246959-A1 BENZIMIDAZOLE DERIVATIVE AND PREPARATION METHOD THEREFOR AND MEDICAL USE THEREOF SHENZHEN SALUBRIS PHARMACEUTICALS CO., LTD. (CN) 2024-07-25 US claimed
US-20240092780-A1 ADDUCTS AND DIMER COMPOUNDS SYNTHESIZED USING GK METHOD ANKH LIFE SCIENCES LIMITED (IE) 2024-03-21 US claimed
US-20240002405-A1 ANTIMICROBIAL COMPOUNDS, SYNTHESIS METHODS, AND USES THEREOF ANKH LIFE SCIENCES LIMITED (IE) 2024-01-04 US claimed
WO-2023235782-A2 ANTIMICROBIAL COMPOUNDS, SYNTHESIS METHODS, AND USES THEREOF ANKH LIFE SCIENCES LIMITED (IE) 2023-12-07 WO claimed
EP-4242202-A1 BENZIMIDAZOLE DERIVATIVE AND PREPARATION METHOD THEREFOR AND MEDICAL USE THEREOF Shenzhen Salubris Pharmaceuticals Co., Ltd. (CN) 2023-09-13 EP claimed
CN-115710281-A Isoxazolo [5,4-b ] pyridine FLT 3inhibitor and preparation method and application thereof 南京中医药大学 2023-02-24 CN claimed
US-20230027361-A1 METTL3 MODULATORS ACCENT THERAPEUTICS, INC. (US) 2023-01-26 US claimed
US-20220372040-A1 METTL3 MODULATORS ACCENT THERAPEUTICS, INC. (US) 2022-11-24 US claimed
CN-115298179-A METTL3 modulators 埃克森特治疗公司 2022-11-04 CN claimed
US-20100317675-A1 6-HETEROCYCLIC-IMIDAZO[1,2-a]PYRIDINE-2-CARBOXAMIDE DERIVATIVES, PREPARATION AND THERAPEUTIC USE THEREOF SANOFI-AVENTIS (FR) 2010-12-16 US claimed
WO-2010102778-A2 SUBSTITUTED 3-AMINOISOXAZOLOPYRIDINES AS KCNQ2/3 MODULATORS Grünenthal GmbH (DE) 2010-09-16 WO claimed
US-20100234419-A1 SUBSTITUTED 3-AMINOISOXAZOLOPYRIDINES AS KCNQ2/3 MODULATORS GRUNENTHAL GMBH (DE) 2010-09-16 US claimed
EP-2225240-A2 DERIVATIVES OF 6-HETEROCYCLIC-IMIDAZOÝL,2-A¨PYRROINE-2-CARBOXAMIDES, PREPARATION THEREOF AND THERAPEUTIC APPLICATION THEREOF Sanofi-Aventis (FR) 2010-09-08 EP claimed
WO-2009106750-A2 DERIVATIVES OF 6-HETEROCYCLIC-IMIDAZO[L,2-A]PYRROINE-2-CARBOXAMIDES, PREPARATION THEREOF AND THERAPEUTIC APPLICATION THEREOF SANOFI-AVENTIS (FR) 2009-09-03 WO claimed
US-20070155749-A1 DERIVATIVES OF 1,4-DIAZABICYCLO[3.2.1]OCTANECARBOXAMIDE, PREPARATION METHOD THEREOF AND USE OF SAME IN THERAPEUTICS SANOFI-AVENTIS (FR) 2007-07-05 US claimed
EP-1709052-A1 DERIVATIVES OF 1,4-DIAZABICYCLO 3.2.1OCTANECARBOXAMIDE, PREPARATION METHOD THEREOF AND USE OF SAME IN THERAPEUTICS Sanofi-Aventis (FR) 2006-10-11 EP claimed
US-20060156486-A1 Keratin dyeing compounds, keratin dyeing compositions containing them, and use thereof THE PROCTER & GAMBLE COMPANY (US) 2006-07-20 US claimed
WO-2005077955-A1 DERIVATIVES OF 1,4-DIAZABICYCLO[3.2.1]OCTANECARBOXAMIDE, PREPARATION METHOD THEREOF AND USE OF SAME IN THERAPEUTICS SANOFI-AVENTIS (FR) 2005-08-25 WO claimed
EP-0227932-A1 Novel fused pyridine compounds, intermediates for the preparation of, and use of said compounds as herbicidal agents AMERICAN CYANAMID COMPANY (US) 1987-07-08 EP claimed