Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23484936 | 0.89 | ALDH1A1 (0.33) | ALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL23484940 | 0.86 | L3MBTL1 (0.35) | ALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL23484926 | 0.84 | L3MBTL1 (0.41) | ALDH1A1 | |
| SCHEMBL23594150 | 0.83 | ALDH1A1 (0.36) | ALDH1A1SMN1; SMN2 | |
| SCHEMBL24926159 | 0.82 | ALDH1A1 (0.33) | ALDH1A1 | |
| SCHEMBL24891050 | 0.81 | L3MBTL1 (0.33) | ALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL13403911 | 0.75 | CPN1 (0.41) | ALDH1A1 | |
| SCHEMBL24891020 | 0.72 | NPC1 (0.57) | ALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL24926161 | 0.72 | L3MBTL1 (0.41) | — | |
| SCHEMBL21946673 | 0.71 | ALDH1A1 (0.35) | ALDH1A1HPGDSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020081450-A1 | BIFUNCTIONAL COMPOUNDS FOR DEGRADING BTK VIA UBIQUITIN PROTEOSOME PATHWAY | NURIX THERAPEUTICS, INC. (US) | 2020-04-23 | — | — | WO | disclosed |