Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.38 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.38 |
| ▸ | S1PR5 | Q9H228 | 2/20 | 0.38 |
| ▸ | HRH2 | P25021 | 4/20 | 0.37 |
| ▸ | HRH1 | P35367 | 4/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.36 |
| ▸ | GPR183 | P32249 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 2/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21947695 | 0.83 | S1PR1 (0.37) | GAAS1PR1S1PR3S1PR5HRH2 | |
| SCHEMBL24926154 | 0.83 | S1PR1 (0.37) | GAAS1PR1S1PR3S1PR5HRH2 | |
| SCHEMBL24927397 | 0.79 | S1PR1 (0.39) | GAAS1PR1S1PR3S1PR5HRH2 | |
| SCHEMBL3761047 | 0.75 | GAA (0.43) | GAAHRH2HRH1HSD17B10ALOX15 | |
| SCHEMBL13367218 | 0.73 | GAA (0.57) | GAAHSD17B10ALOX15TSHRL3MBTL1 | |
| SCHEMBL13804168 | 0.73 | ALDH1A1 (0.48) | TSHRL3MBTL1ALDH1A1MEN1KMT2A | |
| SCHEMBL24891066 | 0.72 | GAA (0.38) | GAAHRH2HRH1HSD17B10ALOX15 | |
| SCHEMBL24773181 | 0.72 | HRH2 (0.53) | GAAHRH2HRH1L3MBTL1GPR183 | |
| SCHEMBL3761133 | 0.71 | SIGMAR1 (0.46) | GAAALDH1A1RECQLPKMSMN1; SMN2 | |
| SCHEMBL3774581 | 0.71 | GAA (0.47) | GAAHSD17B10ALOX15TSHRL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020081450-A1 | BIFUNCTIONAL COMPOUNDS FOR DEGRADING BTK VIA UBIQUITIN PROTEOSOME PATHWAY | NURIX THERAPEUTICS, INC. (US) | 2020-04-23 | — | — | WO | disclosed |