Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.36 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.36 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.35 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29258683 | 0.82 | SLC6A2 (0.41) | SLC6A2SLC6A4SLC18A3OPRM1ALDH1A1 | |
| SCHEMBL13566529 | 0.73 | OPRM1 (0.50) | SLC6A2SLC6A4SLC18A3OPRM1KDM4E | |
| SCHEMBL13566530 | 0.73 | OPRM1 (0.50) | SLC6A2SLC6A4SLC18A3OPRM1KDM4E | |
| SCHEMBL29218400 | 0.73 | OPRM1 (0.47) | SLC6A2SLC6A4SLC18A3OPRM1KDM4E | |
| SCHEMBL21948557 | 0.70 | NOS1 (0.41) | SLC6A2SLC6A4SLC18A3KDM4EALDH1A1 | |
| SCHEMBL18582034 | 0.70 | BCHE (0.41) | SLC18A3ALDH1A1KMT2AMEN1CHRM3 | |
| SCHEMBL18582036 | 0.70 | BCHE (0.41) | SLC18A3ALDH1A1KMT2AMEN1CHRM3 | |
| SCHEMBL20687903 | 0.69 | SLC18A3 (0.56) | SLC6A2SLC6A4SLC18A3ALDH1A1TSHR | |
| SCHEMBL22252483 | 0.69 | SLC18A3 (0.56) | SLC6A2SLC6A4SLC18A3ALDH1A1TSHR | |
| SCHEMBL22273230 | 0.69 | SLC18A3 (0.56) | SLC6A2SLC6A4SLC18A3ALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020081508-A1 | TYK2 INHIBITORS AND USES THEREOF | NIMBUS LAKSHMI, INC. (US) | 2020-04-23 | — | — | WO | disclosed |