Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYMS | P04818 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | USP2 | O75604 | 1/20 | 0.49 |
| ▸ | S100A4 | P26447 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.48 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.48 |
| ▸ | CASP1 | P29466 | 1/20 | 0.48 |
| ▸ | CASP7 | P55210 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | HPGD | P15428 | 5/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.43 |
| ▸ | POLB | P06746 | 3/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.43 |
| ▸ | HSD17B1 | P14061 | 3/20 | 0.42 |
| ▸ | RECQL | P46063 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10048344 | 0.82 | CES1 (0.48) | TYMSKMT2AMEN1USP2S100A4 | |
| SCHEMBL20698451 | 0.81 | ALDH1A1 (0.50) | TYMSKMT2AMEN1USP2S100A4 | |
| SCHEMBL11880591 | 0.76 | PARP1 (0.48) | KMT2AMEN1USP2CASP1CASP7 | |
| SCHEMBL2158711 | 0.76 | TYMS (0.46) | TYMSKMT2AMEN1HSD17B10KDM4E | |
| SCHEMBL30067536 | 0.73 | ALDH1A1 (0.68) | TYMSKMT2AMEN1USP2S100A4 | |
| SCHEMBL254933 | 0.73 | ALDH1A1 (0.68) | TYMSKMT2AMEN1USP2S100A4 | |
| SCHEMBL10018457 | 0.73 | ALDH1A1 (0.41) | TYMSKMT2AMEN1USP2S100A4 | |
| SCHEMBL17032011 | 0.73 | ALDH1A1 (0.54) | KMT2AMEN1USP2HSD17B10KDM4E | |
| SCHEMBL13727049 | 0.71 | TYMS (0.66) | TYMSKMT2AMEN1USP2S100A4 | |
| SCHEMBL13726109 | 0.71 | TYMS (1.00) | TYMSKMT2AMEN1USP2S100A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3640235-A1 | NOVEL PROCESS FOR THE PREPARATION OF CYCLIC PERI-SUCCINOYLACENAPHTHENE AND RELATED 1,4-DIKETO COMPOUNDS | Clariant Plastics & Coatings Ltd (CH) | 2020-04-22 | — | — | EP | disclosed |