Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 1/20 | 0.41 |
| ▸ | MMP2 | P08253 | 1/20 | 0.41 |
| ▸ | MMP9 | P14780 | 1/20 | 0.41 |
| ▸ | MMP8 | P22894 | 1/20 | 0.41 |
| ▸ | MMP13 | P45452 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26024574 | 0.90 | MMP1 (0.41) | MMP1MMP2MMP9MMP8MMP13 | |
| SCHEMBL26024559 | 0.90 | MMP1 (0.43) | MMP1MMP2MMP9MMP8MMP13 | |
| SCHEMBL21949614 | 0.88 | MMP1 (0.42) | MMP1MMP2MMP9MMP8MMP13 | |
| SCHEMBL17059204 | 0.87 | MMP1 (0.42) | MMP1MMP2MMP9MMP8MMP13 | |
| SCHEMBL29531606 | 0.87 | MMP1 (0.42) | MMP1MMP2MMP9MMP8MMP13 | |
| SCHEMBL26024534 | 0.84 | HTT (0.44) | MMP1MMP2MMP9MMP8MMP13 | |
| SCHEMBL30235399 | 0.83 | ALDH1A1 (0.52) | MMP1MMP2MMP9MMP8MMP13 | |
| SCHEMBL30917031 | 0.82 | MMP1 (0.40) | MMP1MMP2MMP9MMP8MMP13 | |
| SCHEMBL19221938 | 0.81 | KDM4E (0.50) | MMP1MMP2MMP9MMP8MMP13 | |
| SCHEMBL21949203 | 0.81 | MMP1 (0.41) | MMP1MMP2MMP9MMP8MMP13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3640248-A1 | AMINOPYRIMIDINE COMPOUND, PREPARATION METHOD THEREFOR AND USE THEREOF | Beijing Adamadle Biotechnology Limited Liability Company (CN) | 2020-04-22 | — | — | EP | disclosed |