Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.46 |
| ▸ | L3MBTL3 | Q96JM7 | 4/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | HTR1A | P08908 | 1/20 | 0.33 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | DRD1 | P21728 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.33 |
| ▸ | DRD3 | P35462 | 1/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | MBTD1 | Q05BQ5 | 1/20 | 0.32 |
| ▸ | PIM1 | P11309 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13395779 | 0.89 | ALDH1A1 (0.51) | ALDH1A1HRH3L3MBTL3L3MBTL1ADRA1A | |
| SCHEMBL26031667 | 0.89 | ALDH1A1 (0.40) | ALDH1A1HRH3L3MBTL3L3MBTL1CYP2D6 | |
| SCHEMBL8266529 | 0.88 | HRH3 (0.38) | ALDH1A1HRH3L3MBTL3L3MBTL1CYP2D6 | |
| SCHEMBL8298097 | 0.83 | HRH3 (0.40) | HRH3CYP2D6CHRM2HTR1AADRA2A | |
| SCHEMBL8298892 | 0.83 | SMN1; SMN2 (0.39) | ALDH1A1HRH3L3MBTL1CYP2D6CHRM2 | |
| SCHEMBL4400116 | 0.80 | ALDH1A1 (0.52) | ALDH1A1L3MBTL3L3MBTL1MBTD1 | |
| SCHEMBL107233 | 0.80 | L3MBTL3 (0.53) | ALDH1A1L3MBTL3L3MBTL1CYP2D6CYP2C19 | |
| SCHEMBL18232026 | 0.79 | PIM1 (0.36) | ALDH1A1HRH3L3MBTL3L3MBTL1CYP2D6 | |
| SCHEMBL13395768 | 0.79 | ALDH1A1 (0.41) | ALDH1A1HRH3L3MBTL3L3MBTL1CYP2D6 | |
| SCHEMBL23815785 | 0.79 | ALDH1A1 (0.52) | ALDH1A1L3MBTL3L3MBTL1MBTD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3640248-A1 | AMINOPYRIMIDINE COMPOUND, PREPARATION METHOD THEREFOR AND USE THEREOF | Beijing Adamadle Biotechnology Limited Liability Company (CN) | 2020-04-22 | — | — | EP | disclosed |