Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR1 | P11362 | 2/20 | 0.44 |
| ▸ | SRC | P12931 | 2/20 | 0.44 |
| ▸ | PKMYT1 | Q99640 | 3/20 | 0.40 |
| ▸ | SLC2A1 | P11166 | 2/20 | 0.40 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.40 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 6/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MAPK10 | P53779 | 2/20 | 0.38 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.38 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21949454 | 0.90 | IRAK4 (0.41) | FGFR1SRCMAPTMAPK1MAPK10 | |
| SCHEMBL21949415 | 0.85 | PYGM (0.43) | FGFR1SRCMAPTMEN1KMT2A | |
| SCHEMBL21949378 | 0.84 | MAPT (0.39) | FGFR1SRCPKMYT1SLC2A1PDGFRB | |
| SCHEMBL21949139 | 0.81 | SYK (0.39) | SRCMAPTMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL21949453 | 0.80 | KMT2A (0.40) | MAPTMEN1KMT2ASMN1; SMN2LMNA | |
| SCHEMBL21949854 | 0.79 | JAK2 (0.39) | MAPTMEN1KMT2ASMN1; SMN2LMNA | |
| SCHEMBL21949142 | 0.78 | SYK (0.40) | FGFR1SRCMAPTMAPK1KDM4E | |
| SCHEMBL21949118 | 0.78 | FGFR1 (0.41) | FGFR1SRCPKMYT1SLC2A1PDGFRB | |
| SCHEMBL21949135 | 0.78 | PYGM (0.41) | WEE1BRD4CSNK2A1 | |
| SCHEMBL21949405 | 0.78 | PYGM (0.44) | FGFR1SRCBRD4EGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3640247-B1 | SYK INHIBITOR AND USE METHOD THEREFOR | CHIA TAI TIANQING PHARMACEUTICAL GROUP CO LTD (CN) | 2022-01-12 | — | — | EP | disclosed |
| EP-3640247-A1 | SYK INHIBITOR AND USE METHOD THEREFOR | Chia Tai Tianqing Pharmaceutical Group Co., Ltd. (CN) | 2020-04-22 | — | — | EP | disclosed |