Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 6/20 | 0.53 |
| ▸ | ESR2 | Q92731 | 6/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | TYR | P14679 | 1/20 | 0.35 |
| ▸ | AR | P10275 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | HTR6 | P50406 | 1/20 | 0.35 |
| ▸ | ESRRG | P62508 | 1/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.33 |
| ▸ | KIF11 | P52732 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23995932 | 0.83 | ESR1 (0.62) | ESR1ESR2KDM4EMEN1KMT2A | |
| SCHEMBL24610439 | 0.79 | ESR1 (0.49) | ESR1ESR2LMNATYR | |
| SCHEMBL7938037 | 0.77 | ESR1 (0.69) | ESR1ESR2KDM4EMEN1KMT2A | |
| SCHEMBL21216068 | 0.77 | ESR1 (0.45) | ESR1ESR2KDM4EMEN1KMT2A | |
| SCHEMBL7929177 | 0.74 | ESR1 (0.64) | ESR1ESR2KDM4EMEN1KMT2A | |
| SCHEMBL7929343 | 0.74 | ESR2 (0.69) | ESR1ESR2KDM4E | |
| SCHEMBL8999933 | 0.73 | ESR1 (0.75) | ESR1ESR2MEN1KMT2ALMNA | |
| SCHEMBL3686864 | 0.73 | ESR1 (1.00) | ESR1ESR2KDM4EMEN1KMT2A | |
| SCHEMBL4560440 | 0.73 | ESR1 (1.00) | ESR1ESR2KDM4EMEN1KMT2A | |
| SCHEMBL21027 | 0.73 | ESR1 (1.00) | ESR1ESR2KDM4EMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10635009-B2 | Electrophotographic photosensitive member, process cartridge, and image forming apparatus | KYOCERA DOCUMENT SOLUTIONS INC. (JP) | 2020-04-28 | — | — | US | disclosed |