SCHEMBL21027

SCHEMBL21027

Oc1ccc(C(c2ccc(O)cc2)(C(F)(F)F)C(F)(F)F)cc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 11/20 1.00
ESR2 Q92731 11/20 1.00
KIF11 P52732 1/20 0.54
CYP3A4 P08684 3/20 0.48
LMNA P02545 2/20 0.48
TYR P14679 2/20 0.48
HPGD P15428 2/20 0.48
HSD17B10 Q99714 2/20 0.48
AR P10275 1/20 0.48
TSHR P16473 1/20 0.48
SLC6A2 P23975 1/20 0.48
SLC6A4 P31645 1/20 0.48
HTR6 P50406 1/20 0.48
ESRRG P62508 1/20 0.48
SLC6A3 Q01959 1/20 0.48
ALDH1A1 P00352 2/20 0.44
KDM4E B2RXH2 1/20 0.44
MEN1 O00255 1/20 0.44
NPC1 O15118 1/20 0.44
CA12 O43570 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4560440 1.00 ESR1 (1.00) ESR1ESR2KIF11CYP3A4LMNA
SCHEMBL3686864 1.00 ESR1 (1.00) ESR1ESR2KIF11CYP3A4LMNA
SCHEMBL30625966 0.97 ESR1 (0.95) ESR1ESR2KIF11CYP3A4LMNA
Potassium SCHEMBL30701764 0.97 ESR1 (0.95) ESR1ESR2KIF11CYP3A4LMNA
SCHEMBL7935379 0.93 ESR1 (0.86) ESR1ESR2KIF11CYP3A4LMNA
SCHEMBL10906373 0.93 ESR1 (0.86) ESR1ESR2KIF11CYP3A4LMNA
SCHEMBL6059770 0.93 ESR1 (0.86) ESR1ESR2KIF11CYP3A4LMNA
SCHEMBL6059489 0.93 ESR1 (0.86) ESR1ESR2KIF11CYP3A4LMNA
SCHEMBL8488305 0.91 ESR1 (0.82) ESR1ESR2KIF11CYP3A4LMNA
SCHEMBL28278720 0.91 ESR1 (0.82) ESR1ESR2KIF11CYP3A4LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 13551 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122080606-A Allyl polyarylester modified bismaleimide resin and preparation method and application thereof 2026-05-26 CN claimed
CN-117181021-B Preparation method of bipolar membrane with same main chain of anion/cation exchange layer JIANG University OF TECHNOLOGY (CN) 2026-05-26 CN claimed
CN-117487536-B Double-shell thermochromic microcapsule as well as preparation method and application thereof Wuhan Zhongke Advanced Material Technology Co.,Ltd. (CN) 2026-05-26 CN claimed
CN-122082140-A Preparation method of low-melting-point liquid crystal polyarylester in-situ reinforced polyethylene fiber 2026-05-26 CN claimed
US-12630470-B2 Polyamideimide film and window cover film including the same SK INNOVATION CO., LTD. (KR) 2026-05-19 US claimed
CN-122060228-A Sound-absorbing rubber material and preparation method thereof 天津智清未来科技有限公司 2026-05-19 CN claimed
CN-122060272-A Puncture-resistant fluororubber for gasket and preparation method and application thereof 浙江欧尔赛斯科技有限公司 2026-05-19 CN claimed
CN-122057385-A Hydrophilic efficient anti-pollution ultrafiltration membrane and preparation method thereof 长春工业大学 2026-05-19 CN claimed
CN-122036501-A Preparation method of fluorine-containing active ester, fluorine-containing active ester modified epoxy resin, preparation method and application thereof 东华大学 2026-05-15 CN claimed
CN-122037252-A Preparation method of middle-layer leakage-free high-temperature gas filter pulse diaphragm 上海钱丰新材料有限公司 2026-05-15 CN claimed
US-4346211-A IMPROVED HEAT DISTORTION CHARACTERISTICS MOBAY CHEMICAL CORPORATION (US) 1982-08-24 US claimed
US-4287320-A CURABLE, ALSO CONTAINING AN AROMATIC ALCOHOL OR AMINE, AND A QUATERNARY AMMONIUM OR PHOSPHONIUM COMPOUND MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1981-09-01 US claimed
EP-0029111-A1 Thermoplastic aromatic copolycarbonates, process for their preparation from 2,2-bis(4-hydroxyphenyl)-1,1,1,3,3,3-hexafluor propane and their use Mobay Chemical Corporation (US) 1981-05-27 EP claimed
EP-0004087-B1 EPICHLORHYDRIN POLYMER ELASTOMERIC COMPOSITION AND LAYERED PRODUCTS COMPRISING A LAYER OBTAINED FROM SAID COMPOSITION AND A FLUOROELASTOMER LAYER Daikin Kogyo Co., Ltd. (JP) 1981-01-28 EP claimed
US-4196255-A EPICHLOROHYDRIN ELASTOMER, DIVALENT METAL OXIDE OR HYDROXIDE, FLUOROPOLYOL, BASIC NITROGEN OR PHOSPHORUS COMPOUND DAIKIN KOGYO CO., LTD. (JP) 1980-04-01 US claimed
US-4188352-A Elastomeric composition comprising fluoroelastomer and epicholorohydrin elastomer DAIKIN KOGYO CO., LTD. (JP) 1980-02-12 US claimed
EP-0004087-A1 Epichlorhydrin polymer elastomeric composition and layered products comprising a layer obtained from said composition and a fluoroelastomer layer Daikin Kogyo Co., Ltd. (JP) 1979-09-19 EP claimed
US-4146532-A Fluoroelastomer composition with diazobicycloundecenium DAIKIN KOGYO CO., LTD. (JP) 1979-03-27 US claimed
US-4141874-A Fluorine-containing elastomeric copolymers, process for preparing the same and composition containing the same DAIKIN KOGYO CO., LTD. (JP) 1979-02-27 US claimed
US-3951914-A Process for preparing poly(1,4-benzamide) in cyclic sulfone media E. I. DU PONT DE NEMOURS AND COMPANY (US) 1976-04-20 US claimed