Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 5/20 | 0.36 |
| ▸ | PANK3 | Q9H999 | 1/20 | 0.30 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21857732 | 0.86 | AR (0.45) | ARPANK3SIRT6 | |
| SCHEMBL29913457 | 0.86 | AR (0.45) | ARPANK3SIRT6 | |
| SCHEMBL21953171 | 0.72 | FPR2 (0.37) | PANK3 | |
| SCHEMBL31009069 | 0.72 | FPR2 (0.37) | PANK3 | |
| SCHEMBL31657833 | 0.72 | FPR2 (0.37) | PANK3 | |
| SCHEMBL9900172 | 0.64 | AR (0.56) | AR | |
| SCHEMBL18695380 | 0.63 | BACE1 (0.32) | — | |
| SCHEMBL23750019 | 0.61 | PANK3 (0.31) | PANK3SIRT6 | |
| SCHEMBL21580615 | 0.61 | AR (0.51) | AR | |
| SCHEMBL1190896 | 0.61 | AR (0.64) | AR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021156584-A1 | KV3 MODULATORS | AUTIFONY THERAPEUTICS LIMITED (GB) | 2021-08-12 | — | — | WO | disclosed |
| WO-2020079422-A1 | NOVEL COMPOUNDS | AUTIFONY THERAPEUTICS LIMITED (GB) | 2020-04-23 | — | — | WO | disclosed |