SCHEMBL21857732

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL29913457	1.00	AR (0.45)	ARPOLBALDH1A1RAB9ASMN1; SMN2
	SCHEMBL21953172	0.86	AR (0.36)	ARSIRT6PANK3
	SCHEMBL21953171	0.82	FPR2 (0.37)	ALDH1A1RAB9APANK3
	SCHEMBL31009069	0.82	FPR2 (0.37)	ALDH1A1RAB9APANK3
	SCHEMBL31657833	0.82	FPR2 (0.37)	ALDH1A1RAB9APANK3
	SCHEMBL9900172	0.73	AR (0.56)	ARPOLBALDH1A1RAB9ASMN1; SMN2
	SCHEMBL21580615	0.73	AR (0.51)	ARALDH1A1SMN1; SMN2
	SCHEMBL21610251	0.72	AR (0.43)	ARPOLBALDH1A1RAB9ASMN1; SMN2
	SCHEMBL31572814	0.71	AR (0.45)	ARALDH1A1RAB9ASMN1; SMN2
	SCHEMBL1772990	0.70	AR (0.56)	ARPOLBRAB9ASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.