SCHEMBL219553

SCHEMBL219553

CC(=O)[C@@]1(n2cnc3c(N)ncnc32)O[C@H](CO)[C@@H](O)[C@H]1O

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ADORA3 P0DMS8 5/20 0.49
ADORA2A P29274 3/20 0.49
PI4KA P42356 2/20 0.49
PI4K2B Q8TCG2 2/20 0.49
PI4K2A Q9BTU6 2/20 0.49
PI4KB Q9UBF8 2/20 0.49
SLC28A1 O00337 2/20 0.49
ADORA1 P30542 2/20 0.49
DPP4 P27487 1/20 0.49
MEN1 O00255 1/20 0.49
MAP3K7 O43318 1/20 0.49
SLC28A2 O43868 1/20 0.49
GAPDH P04406 1/20 0.49
MAPK1 P28482 1/20 0.49
ADORA2B P29275 1/20 0.49
STAT6 P42226 1/20 0.49
KMT2A Q03164 1/20 0.49
SMN1; SMN2 Q16637 1/20 0.49
DOT1L Q8TEK3 1/20 0.49
SLC29A1 Q99808 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Phosphoric Acid SCHEMBL474409 0.96 ADORA1 (0.48) ADORA3ADORA2API4KAPI4K2BPI4K2A
Acetaldehyde SCHEMBL27678170 0.96 ADORA3 (0.48) ADORA3ADORA2API4KAPI4K2BPI4K2A
SCHEMBL5742074 0.91 EGFR (0.49) ADORA3ADORA2API4KAPI4K2BPI4K2A
SCHEMBL2463541 0.90 ADORA3 (0.50) ADORA3ADORA2API4KAPI4K2BPI4K2A
SCHEMBL29655156 0.90 ADORA3 (0.50) ADORA3ADORA2API4KAPI4K2BPI4K2A
SCHEMBL28215296 0.89 ADORA3 (0.49) ADORA3ADORA2API4KAPI4K2BPI4K2A
SCHEMBL1066702 0.89 PI4KA (0.46) ADORA3ADORA2API4KAPI4K2BPI4K2A
SCHEMBL2761283 0.89 PI4KA (0.47) ADORA3ADORA2API4KAPI4K2BPI4K2A
SCHEMBL27653575 0.88 ADORA3 (0.48) ADORA3ADORA2API4KAPI4K2BPI4K2A
SCHEMBL27455665 0.88 PI4KA (0.39) ADORA3ADORA2API4KAPI4K2BPI4K2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 171 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118580307-B Pro.AH8 acetyl hexapeptide-8 with tightening and anti-wrinkle effects, and preparation method and application thereof 广东合鸣生物科技有限公司 2025-05-27 CN claimed
CN-118580307-A Pro.AH8 acetyl hexapeptide-8 with tightening and anti-wrinkle effects, and preparation method and application thereof 广东合鸣生物科技有限公司 2024-09-03 CN claimed
CN-113521091-A Pharmaceutical composition for preventing or treating heart diseases and application thereof 睿纳(珠海横琴)生物科技有限公司 2021-10-22 CN claimed
US-11149271-B2 Method and pharmaceutical composition for treating cancer INCREASEPHARM (HK) LIMITED (HK) 2021-10-19 US claimed
CN-110870871-B Methods and pharmaceutical compositions for treating cancer 澳门科技大学 2021-09-07 CN claimed
WO-2021035391-A1 USE OF TRANSFER RNA MOLECULE AND FRAGMENT THEREOF IN PREVENTION OR TREATMENT OF HEART DISEASE 澳门科技大学 2021-03-04 WO claimed
US-20210052630-A1 Methods and Compositions for Preventing or Treating Heart Disease MACAU UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) 2021-02-25 US claimed
CN-111419867-A Use of transport RNA molecules and fragments thereof for preventing or treating cardiac diseases 澳门科技大学 2020-07-17 CN claimed
CN-110870871-A Methods and pharmaceutical compositions for treating cancer 澳门科技大学 2020-03-10 CN claimed
US-20200071695-A1 METHOD AND PHARMACEUTICAL COMPOSITION FOR TREATING CANCER INCREASEPHARM (HK) LIMITED (HK) 2020-03-05 US claimed
US-8088752-B2 Methods for metabolic modulation VDF FUTURECEUTICALS, INC. (US) 2012-01-03 US claimed
WO-2026107144-A1 RNA SEQUENCE FOR EXPRESSING PROTEIN IN CARDIOMYOCYTES ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI (US) 2026-05-21 WO disclosed
CN-118580307-B Pro.AH8 acetyl hexapeptide-8 with tightening and anti-wrinkle effects, and preparation method and application thereof 广东合鸣生物科技有限公司 2025-05-27 CN disclosed
WO-2025072615-A1 IMPROVED METHODS OF MAKING RNA BY SPLINTED LIGATION AND COMPOSITIONS THEREOF ORBITAL THERAPEUTICS, INC. (US) 2025-04-03 WO disclosed
CN-118580307-A Pro.AH8 acetyl hexapeptide-8 with tightening and anti-wrinkle effects, and preparation method and application thereof 广东合鸣生物科技有限公司 2024-09-03 CN disclosed
US-6552182-B2 Gel or viscous liquid of polymer compounds and water, water/ alcohol mixtures and polar aprotic solvents is coated on the nucleoside and irradiated NIGU CHEMIE GMBH (DE) 2003-04-22 US disclosed
US-20020053508-A1 Method for photolytically deprotecting immobilized nucleoside derivatives, especially in the production of DNA chips NIGU CHEMIE GMBH 2002-05-09 US disclosed
EP-0935466-A1 METHOD AND COMPOSITION FOR INHIBITING CELLULAR IRREVERSIBLE CHANGES DUE TO STRESS Galileo Laboratories, Inc. (US) 1999-08-18 EP disclosed
US-5801159-A TREATMENT OF HYPOXIA BY ADMINISTERING PURINE DERIVATIVE, ELECTRON ACCEPTOR COMPOUNDS, AMINO ACIDS GALILEO LABORATORIES, INC. (US) 1998-09-01 US disclosed
WO-1997030713-A1 METHOD AND COMPOSITION FOR INHIBITING CELLULAR IRREVERSIBLE CHANGES DUE TO STRESS GALILEO LABORATORIES, INC. (US) 1997-08-28 WO disclosed