Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8504406 | 0.70 | ELANE (0.31) | ELANE | |
| SCHEMBL14346958 | 0.67 | HDAC4 (0.35) | — | |
| SCHEMBL1837423 | 0.64 | ELANE (0.39) | ELANE | |
| SCHEMBL25489131 | 0.62 | PIK3CG (0.40) | — | |
| SCHEMBL13475364 | 0.62 | PIK3CG (0.40) | — | |
| SCHEMBL6476727 | 0.61 | LMNA (0.36) | — | |
| SCHEMBL4300065 | 0.61 | LMNA (0.36) | — | |
| SCHEMBL8193269 | 0.60 | HDAC4 (0.34) | — | |
| SCHEMBL18760105 | 0.54 | HDAC4 (0.47) | — | |
| SCHEMBL15116409 | 0.53 | LMNA (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3658542-B1 | PREPARATION OF SUBSTITUTED 3-ARYL-5-TRIFLUOROMETHYL-1,2,4-OXADIAZOLES | BASF SE (DE) | 2022-09-07 | — | — | EP | disclosed |
| US-11021452-B2 | Preparation of substituted 3-aryl-5-trifluoromethyl-1,2,4-oxadiazoles | BASF SE (DE) | 2021-06-01 | — | — | US | disclosed |
| US-20200157064-A1 | Preparation of substituted 3-aryl-5-trifluoromethyl-1,2,4-oxadiazoles | BASF SE (DE) | 2020-05-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11021452-B2 | Preparation of substituted 3-aryl-5-trifluoromethyl-1,2,4-oxadiazoles | AZI2, FLI1, OXA1L | ELANE 3590/4885 |
| US-20200157064-A1 | Preparation of substituted 3-aryl-5-trifluoromethyl-1,2,4-oxadiazoles | AZI2, FLI1, OXA1L | ELANE 3590/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.