SCHEMBL4300065

SCHEMBL4300065

FC(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)c1nc(C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)F)nc(C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)F)n1

nearest known ligand 0.36

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
▸ LMNA P02545 1/20 0.36
▸ THRB P10828 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6476727 1.00 LMNA (0.36) LMNATHRB
SCHEMBL8504406 0.88 ELANE (0.31) —
SCHEMBL17413752 0.76 ALDH1A1 (0.33) —
SCHEMBL19327455 0.74 CCNE2 (0.35) —
SCHEMBL9722408 0.72 LMNA (0.35) LMNA
SCHEMBL8626595 0.72 LMNA (0.35) LMNA
SCHEMBL25012747 0.70 — —
SCHEMBL25013353 0.70 — —
SCHEMBL62622 0.69 LMNA (0.61) LMNATHRB
SCHEMBL25012746 0.69 — —

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2113301-B1 Preparation of microbeads SONY CORP (JP) 2016-05-11 — — EP disclosed
US-8409706-B2 Preparation process of microbeads, and microbeads SONY CORPORATION (JP) 2013-04-02 — — US disclosed
US-20090274908-A1 PREPARATION PROCESS OF MICROBEADS, AND MICROBEADS SONY CORPORATION (JP) 2009-11-05 — — US disclosed
EP-2113301-A1 Preparation of microbeads, and microbeads Sony Corporation (JP) 2009-11-04 — — EP disclosed
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