Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.62 |
| ▸ | LMNA | P02545 | 3/20 | 0.61 |
| ▸ | AKR1B10 | O60218 | 2/20 | 0.56 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.56 |
| ▸ | CA12 | O43570 | 2/20 | 0.56 |
| ▸ | CA4 | P22748 | 2/20 | 0.56 |
| ▸ | CA6 | P23280 | 2/20 | 0.56 |
| ▸ | CA5A | P35218 | 2/20 | 0.56 |
| ▸ | CA7 | P43166 | 2/20 | 0.56 |
| ▸ | CA9 | Q16790 | 2/20 | 0.56 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.56 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.55 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.55 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | TTR | P02766 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1070423 | 0.85 | HCAR2 (0.71) | HCAR2ALDH1A1LMNAAKR1B10AKR1B1 | |
| SCHEMBL1070426 | 0.85 | HCAR2 (0.71) | HCAR2ALDH1A1LMNAAKR1B10AKR1B1 | |
| SCHEMBL337504 | 0.83 | HCAR2 (0.89) | HCAR2ALDH1A1LMNAAKR1B10AKR1B1 | |
| SCHEMBL9395526 | 0.83 | HCAR2 (0.69) | HCAR2ALDH1A1LMNAAKR1B10AKR1B1 | |
| SCHEMBL357565 | 0.83 | HCAR2 (0.89) | HCAR2ALDH1A1LMNAAKR1B10AKR1B1 | |
| SCHEMBL337503 | 0.83 | HCAR2 (0.89) | HCAR2ALDH1A1LMNAAKR1B10AKR1B1 | |
| Propene SCHEMBL28200015 | 0.83 | HCAR2 (0.59) | HCAR2ALDH1A1LMNAAKR1B10AKR1B1 | |
| SCHEMBL10920042 | 0.82 | HCAR2 (0.57) | HCAR2ALDH1A1LMNAAKR1B10AKR1B1 | |
| SCHEMBL26288 | 0.82 | HCAR2 (0.67) | HCAR2ALDH1A1LMNAAKR1B10AKR1B1 | |
| SCHEMBL27659194 | 0.82 | HCAR2 (0.85) | HCAR2ALDH1A1LMNAAKR1B10AKR1B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 295 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4273147-A1 | SUBSTITUTED SPIROLACTAMS, SALTS THEREOF AND THEIR USE AS HERBICIDALLY ACTIVE SUBSTANCES | Bayer Aktiengesellschaft (DE) | 2023-11-08 | — | — | EP | claimed |
| US-11274083-B2 | Substituted thiophenyl uracils, salts thereof and the use thereof as herbicidal agents | SYNGENTA CROP PROTECTION AG (CH) | 2022-03-15 | — | — | US | claimed |
| CN-114106041-A | Process for synthesizing triphenylphosphine halogenated salt by solvent-free reaction method | 江苏宝众宝达药业股份有限公司 | 2022-03-01 | — | — | CN | claimed |
| EP-3728235-B1 | SUBSTITUTED THIOPHENYLURACILS , THEIR SALTS AND USE OF SAID COMPOUNDS AS HERBICIDAL AGENTS | SYNGENTA CROP PROTECTION AG (CH) | 2022-02-09 | — | — | EP | claimed |
| US-20210087151-A1 | SUBSTITUTED THIOPHENYL URACILS, SALTS THEREOF AND THE USE THEREOF AS HERBICIDAL AGENTS | SYNGENTA CROP PROTECTION AG (CH) | 2021-03-25 | — | — | US | claimed |
| US-20200390100-A1 | SUBSTITUTED N-HETEROCYCLYL- AND N-HETEROARYL-TETRAHYDROPYRIMIDINONES AND THE SALTS THEREOF, AND THE USE OF SAME AS HERBICIDAL ACTIVE SUBSTANCES | BAYER AG (DE) | 2020-12-17 | — | — | US | claimed |
| EP-3728235-A1 | SUBSTITUTED THIOPHENYL URACILS, SALTS THEREOF AND THE USE THEREOF AS HERBICIDAL AGENTS | Syngenta Crop Protection AG (CH) | 2020-10-28 | — | — | EP | claimed |
| EP-3728214-A1 | SUBSTITUTED N-HETEROCYCLYL- AND N-HETEROARYL-TETRAHYDROPYRIMIDINONES AND THE SALTS THEREOF, AND THE USE OF SAME AS HERBICIDAL ACTIVE SUBSTANCES | Bayer Aktiengesellschaft (DE) | 2020-10-28 | — | — | EP | claimed |
| CN-111727185-A | Substituted N-heterocyclyl-and N-heteroaryltetrahydropyrimidines and their salts and their use as herbicidal active substances | 拜耳公司 | 2020-09-29 | — | — | CN | claimed |
| US-20200079765-A1 | SUBSTITUTED HETEROARYL PYRROLONES AND SALTS THEREOF AND USE THEREOF AS HERBICIDAL ACTIVE SUBSTANCES | BAYER AKTIENGESELLSCHAFT (DE) | 2020-03-12 | — | — | US | claimed |
| EP-0408384-A1 | N,N'-dicarboxymethyl, N,N'-dicarbamoylmethyl diaminoalkane derivatives and their use in pharmaceutical compositions. | BTG INTERNATIONAL LIMITED (GB) | 1991-01-16 | — | — | EP | claimed |
| EP-0197752-B1 | PHARMACEUTICAL COMPOSITIONS | NATIONAL RESEARCH DEVELOPMENT CORPORATION (GB) | 1990-09-12 | — | — | EP | claimed |
| US-4902714-A | N,N'-DIPROPARGYLOXYCARBONYLMETHYL-N,N'-DIAMINOCARBONYLMETHYL -1,2-DIAMINOPROPANE | NATIONAL RESEARCH DEVELOPMENT CORPORATION (GB) | 1990-02-20 | — | — | US | claimed |
| US-4755619-A | Pharmaceutical compositions | NATIONAL RESEARCH DEVELOPMENT CORPORATION (GB) | 1988-07-05 | — | — | US | claimed |
| EP-0197752-A2 | Pharmaceutical compositions | NATIONAL RESEARCH DEVELOPMENT CORPORATION (GB) | 1986-10-15 | — | — | EP | claimed |
| EP-0027599-B1 | CEPHEM COMPOUNDS, PROCESSES FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1984-10-03 | — | — | EP | claimed |
| US-4413000-A | BACTERICIDES | BEECHAM GROUP LIMITED (GB) | 1983-11-01 | — | — | US | claimed |
| US-4381299-A | 7-Amino-thiadiazole oxyimino derivatives of cephem and cepham compounds | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1983-04-26 | — | — | US | claimed |
| US-4331665-A | ANTIBIOTICS, BACTERICIDES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1982-05-25 | — | — | US | claimed |
| EP-0027599-A2 | Cephem compounds, processes for their preparation and pharmaceutical compositions containing them | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1981-04-29 | — | — | EP | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200390100-A1 | SUBSTITUTED N-HETEROCYCLYL- AND N-HETEROARYL-TETRAHYDROPYRIMIDINONES AND THE SALTS THEREOF, AND THE USE OF SAME AS HERBICIDAL ACTIVE SUBSTANCES | DDT, NOTUM, AGPS | HCAR2 675/4885ALDH1A1 201/4885LMNA 3862/4885 |
| US-11274083-B2 | Substituted thiophenyl uracils, salts thereof and the use thereof as herbicidal agents | UNG, TYMP, TYMS | HCAR2 2986/4885ALDH1A1 133/4885LMNA 4853/4885 |
| US-20210087151-A1 | SUBSTITUTED THIOPHENYL URACILS, SALTS THEREOF AND THE USE THEREOF AS HERBICIDAL AGENTS | UNG, TYMP, TYMS | HCAR2 2986/4885ALDH1A1 133/4885LMNA 4853/4885 |
| US-20200079765-A1 | SUBSTITUTED HETEROARYL PYRROLONES AND SALTS THEREOF AND USE THEREOF AS HERBICIDAL ACTIVE SUBSTANCES | DDT, HPD, PAH | HCAR2 1254/4885ALDH1A1 401/4885LMNA 4592/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.