Sugi Predict

Sugi Predict / Compounds / SCHEMBL219603

SCHEMBL219603

SCHEMBL219603

CC(C)(C)OC(=O)N(CC(=O)O)c1ccccc1

nearest known ligand 0.49

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
▸ SMN1; SMN2 Q16637 2/20 0.49
▸ CYP2C19 P33261 2/20 0.49
▸ MEN1 O00255 2/20 0.49
▸ KMT2A Q03164 2/20 0.49
▸ CYP3A4 P08684 1/20 0.49
▸ CYP2C9 P11712 1/20 0.49
▸ ALDH1A1 P00352 2/20 0.44
▸ TSHR P16473 2/20 0.44
▸ GLA P06280 1/20 0.44
▸ TP53 P04637 1/20 0.44
▸ F2 P00734 2/20 0.42
▸ HIF1A Q16665 1/20 0.41
▸ L3MBTL1 Q9Y468 2/20 0.40
▸ GSTO1 P78417 1/20 0.40
▸ MLYCD O95822 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Dioxane SCHEMBL10470269 0.91 SMN1; SMN2 (0.42) SMN1; SMN2CYP2C19MEN1KMT2ACYP3A4
SCHEMBL6607125 0.91 GSTO1 (0.42) SMN1; SMN2CYP2C19MEN1KMT2ACYP3A4
SCHEMBL5967047 0.90 MEN1 (0.41) SMN1; SMN2CYP2C19MEN1KMT2ACYP3A4
SCHEMBL17974957 0.89 MEN1 (0.47) SMN1; SMN2CYP2C19MEN1KMT2ACYP3A4
SCHEMBL10470268 0.88 SMN1; SMN2 (0.39) SMN1; SMN2CYP2C19MEN1KMT2ACYP3A4
SCHEMBL895556 0.87 MLYCD (0.39) SMN1; SMN2CYP2C19MEN1KMT2ACYP3A4
SCHEMBL6295798 0.87 MLYCD (0.48) SMN1; SMN2CYP2C19MEN1KMT2ACYP3A4
SCHEMBL4423507 0.87 MEN1 (0.46) SMN1; SMN2CYP2C19MEN1KMT2ACYP3A4
SCHEMBL1624562 0.87 MEN1 (0.50) SMN1; SMN2CYP2C19MEN1KMT2ACYP3A4
SCHEMBL4664640 0.86 SMN1; SMN2 (0.45) SMN1; SMN2CYP2C19MEN1KMT2ACYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 943 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250241922-A1 ANTI-INFLAMMATORY COUPLING COMPOUND DRUG, AND PREPARATION METHOD THEREFOR AND USE THEREOF COVAL BIOPHARMA (SHANGHAI)CO., LTD. (CN) 2025-07-31 — — US claimed
US-20250241921-A1 ANTI-INFLAMMATORY COUPLING COMPOUND DRUG, AND PREPARATION METHOD THEREFOR AND USE THEREOF COVAL BIOPHARMA (SHANGHAI)CO., LTD. (CN) 2025-07-31 — — US claimed
US-20240197741-A1 EXTERNAL ANTI-INFLAMMATORY COUPLING COMPOUND DRUG, AND PREPARATION METHOD THEREFOR AND USE THEREOF COVAL BIOPHARMA(SHANGHAI)CO., LTD. (CN) 2024-06-20 — — US claimed
CN-117355527-B Anti-inflammatory coupling compound medicine and preparation method and application thereof 上海椿安生物医药科技有限公司 2024-06-07 — — CN claimed
EP-4357346-A1 EXTERNAL ANTI-INFLAMMATORY COUPLING COMPOUND DRUG, AND PREPARATION METHOD THEREFOR AND USE THEREOF Coval Biopharma (Shanghai) Co., Ltd. (CN) 2024-04-24 — — EP claimed
CN-117777002-A Asymmetric synthesis method of 3, 3-disubstituted oxindole derivative 华南理工大学 2024-03-29 — — CN claimed
CN-117624061-A Production process of oxaagoli sodium 宣城美诺华药业有限公司 2024-03-01 — — CN claimed
CN-117355527-A External anti-inflammatory coupling compound medicine and preparation method and application thereof 上海椿安生物医药科技有限公司 2024-01-05 — — CN claimed
WO-2023001045-A9 EXTERNAL ANTI-INFLAMMATORY COUPLING COMPOUND DRUG, AND PREPARATION METHOD THEREFOR AND USE THEREOF 上海椿安生物医药科技有限公司 2023-10-26 — — WO claimed
CN-116874803-A Antibacterial dendritic polyester polymer and preparation method and application thereof 清华大学深圳国际研究生院 2023-10-13 — — CN claimed
CN-112500361-B Preparation method of (S) -4-phenyl-2-oxazolidinone 甘肃瀚聚药业有限公司 2023-05-12 — — CN claimed
WO-2023001045-A1 EXTERNAL ANTI-INFLAMMATORY COUPLING COMPOUND DRUG, AND PREPARATION METHOD THEREFOR AND USE THEREOF 上海椿安生物医药科技有限公司 2023-01-26 — — WO claimed
CN-112194638-B Aniline anhydride, preparation method thereof and polyamino acid graft chain 苏州大学 2022-07-19 — — CN claimed
CN-110981887-B Dihydroartemisinin compounds, and preparation method and medical application thereof 延边大学 2022-05-17 — — CN claimed
CN-112500361-A Preparation method of (S) -4-phenyl-2-oxazolidinone 甘肃瀚聚药业有限公司 2021-03-16 — — CN claimed
CN-112194638-A Aniline anhydride, preparation method thereof and polyamino acid graft chain 苏州大学 2021-01-08 — — CN claimed
CN-112127157-A Polyamino acid graft modified water-repellent fabric and preparation method thereof 苏州大学 2020-12-25 — — CN claimed
US-9828334-B2 Process for preparing levomilnacipran OLON S.P.A. (IT) 2017-11-28 — — US claimed
CN-104910039-A Functional phenylacetylene compound and preparation method thereof UNIV HARBIN ENG 2015-09-16 — — CN claimed
CN-102432526-A Chiral 2',5-dicarbonyl-3-aryl spiro[cyclohexane-1,3'-indole]-2,2-dinitrile derivative and preparation method thereof UNIV SOOCHOW 2012-05-02 — — CN claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250241921-A1 ANTI-INFLAMMATORY COUPLING COMPOUND DRUG, AND PREPARATION METHOD THEREFOR AND USE THEREOF JAK1, TNF, CYP4A11 SMN1; SMN2 4882/4885CYP2C19 74/4885MEN1 4000/4885
US-20250241922-A1 ANTI-INFLAMMATORY COUPLING COMPOUND DRUG, AND PREPARATION METHOD THEREFOR AND USE THEREOF JAK1, TNF, CYP4A11 SMN1; SMN2 4882/4885CYP2C19 74/4885MEN1 4000/4885
US-20240197741-A1 EXTERNAL ANTI-INFLAMMATORY COUPLING COMPOUND DRUG, AND PREPARATION METHOD THEREFOR AND USE THEREOF TNF, CYP4A11, JAK1 SMN1; SMN2 4883/4885CYP2C19 83/4885MEN1 4096/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.