Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.49 |
| ▸ | VCAM1 | P19320 | 4/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.37 |
| ▸ | MERTK | Q12866 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2950121 | 0.93 | VCAM1 (0.50) | TDP1VCAM1HPGDALDH1A1GPR35 | |
| SCHEMBL21957846 | 0.93 | VCAM1 (0.50) | TDP1VCAM1HPGDALDH1A1GPR35 | |
| Nitrogen SCHEMBL9816717 | 0.84 | TDP1 (0.61) | TDP1HPGDALDH1A1GPR35KDM4E | |
| SCHEMBL58157 | 0.84 | TDP1 (0.65) | TDP1HPGDALDH1A1GPR35KDM4E | |
| SCHEMBL28282595 | 0.84 | TDP1 (0.65) | TDP1HPGDALDH1A1GPR35KDM4E | |
| SCHEMBL29460277 | 0.84 | TDP1 (0.65) | TDP1HPGDALDH1A1GPR35KDM4E | |
| SCHEMBL618153 | 0.80 | TDP1 (0.54) | TDP1VCAM1HPGDALDH1A1GPR35 | |
| SCHEMBL894816 | 0.80 | TDP1 (0.60) | TDP1VCAM1HPGDALDH1A1MAPT | |
| SCHEMBL272708 | 0.80 | TDP1 (0.60) | TDP1VCAM1HPGDALDH1A1MAPT | |
| SCHEMBL30583791 | 0.80 | TDP1 (0.60) | TDP1VCAM1HPGDALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020102716-A1 | PROCESS FOR PREPARATION OF 2,6-DICHLOROBENZONITRILE | ARYSTA LIFESCIENCE INC. (US) | 2020-05-22 | — | — | WO | disclosed |