Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VCAM1 | P19320 | 4/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.45 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | MERTK | Q12866 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21957846 | 1.00 | VCAM1 (0.50) | VCAM1HPGDTDP1GPR35ALDH1A1 | |
| SCHEMBL21961905 | 0.93 | TDP1 (0.49) | VCAM1HPGDTDP1GPR35ALDH1A1 | |
| SCHEMBL618153 | 0.86 | TDP1 (0.54) | VCAM1HPGDTDP1GPR35ALDH1A1 | |
| SCHEMBL13982690 | 0.83 | HPGD (0.47) | VCAM1HPGDTDP1GPR35ALDH1A1 | |
| SCHEMBL8313813 | 0.83 | VCAM1 (0.56) | VCAM1HPGDTDP1ALDH1A1MAPK1 | |
| Dichlobenil SCHEMBL7810801 | 0.81 | GPR35 (0.66) | VCAM1HPGDTDP1GPR35ALDH1A1 | |
| SCHEMBL9489473 | 0.80 | VCAM1 (0.47) | VCAM1HPGDTDP1ALDH1A1KDM4E | |
| SCHEMBL13982723 | 0.80 | HPGD (0.45) | HPGDTDP1GPR35ALDH1A1KDM4E | |
| SCHEMBL30694393 | 0.79 | VCAM1 (0.47) | VCAM1HPGDTDP1GPR35ALDH1A1 | |
| SCHEMBL220318 | 0.79 | VCAM1 (0.47) | VCAM1HPGDTDP1GPR35ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 116 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11708322-B2 | Process for preparation of 2,6-dichlorobenzonitrile | ARYSTA LIFESCIENCE INC. (US) | 2023-07-25 | — | — | US | claimed |
| CN-113038835-B | Preparation method of 2, 6-dichlorobenzonitrile | 爱利思达生命科学有限公司 | 2023-03-28 | — | — | CN | claimed |
| CN-113038835-A | Preparation method of 2, 6-dichlorobenzonitrile | 爱利思达生命科学有限公司 | 2021-06-25 | — | — | CN | claimed |
| WO-2020102716-A1 | PROCESS FOR PREPARATION OF 2,6-DICHLOROBENZONITRILE | ARYSTA LIFESCIENCE INC. (US) | 2020-05-22 | — | — | WO | claimed |
| US-20200157043-A1 | PROCESS FOR PREPARATION OF 2,6-DICHLOROBENZONITRILE | ARYSTA LIFESCIENCE INC. (US) | 2020-05-21 | — | — | US | claimed |
| CN-111116399-A | Process for producing 2, 6-difluorobenzamide | 杨向党 | 2020-05-08 | — | — | CN | claimed |
| CN-1107690-C | Bimaleimide copolymerizing modifier and its preparing process | UNIV SICHUAN UNION (CN) | 2003-05-07 | — | — | CN | claimed |
| US-6336963-B1 | INK COMPOSITION COMPRISING INK VEHICLE COMPRISING FIRST NITRILE COMPOUND HAVING FIRST VISCOSITY AT MELT TEMPERATURE, VISCOSITY MODIFIER COMPRISING SECOND NITRILE COMPOUND HAVING LOWER VISCOSITY AT MELT TEMPERATURE, COLORANT | XEROX CORPORATION | 2002-01-08 | — | — | US | claimed |
| CN-1251848-A | Bimaleimide copolymerizing modifier and its preparing process | UNIV SICHUAN UNION (CN) | 2000-05-03 | — | — | CN | claimed |
| EP-0354444-B1 | PROCESS FOR THE INTRODUCTION OF FLUORINE ON AROMATIC NUCLEUS BY NUCLEOPHILIC EXCHANGE | BAYER AG (DE) | 1993-01-20 | — | — | EP | claimed |
| EP-0243000-B1 | POLYCYANOARYL ETHER, METHOD FOR PREPARING THE SAME AND USES THEREOF | IDEMITSU KOSAN COMPANY LIMITED (JP) | 1990-10-03 | — | — | EP | claimed |
| US-4959487-A | NITROAROMATIC HALIDE | IDEMITSU KOSAN CO., LTD. (JP) | 1990-09-25 | — | — | US | claimed |
| US-4780559-A | Process for preparing organic fluorides | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1988-10-25 | — | — | US | claimed |
| EP-0243000-A1 | Polycyanoaryl ether, method for preparing the same and uses thereof | IDEMITSU KOSAN COMPANY LIMITED (JP) | 1987-10-28 | — | — | EP | claimed |
| EP-0015427-B1 | PROCESS FOR PRODUCING 2-CHLORO-6-NITROBENZONITRILE | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 1983-01-12 | — | — | EP | claimed |
| US-4285883-A | Process for producing 2-chloro-6-nitrobenzonitrile | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 1981-08-25 | — | — | US | claimed |
| EP-0006999-B1 | A PROCESS FOR THE PRODUCTION OF 2-CHLOROBENZONITRILE DERIVATIVES | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 1981-04-01 | — | — | EP | claimed |
| US-4225534-A | FROM CHLORINATED 2-NITROBENZONITRILES | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 1980-09-30 | — | — | US | claimed |
| EP-0015427-A1 | Process for producing 2-chloro-6-nitrobenzonitrile | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 1980-09-17 | — | — | EP | claimed |
| EP-0006999-A1 | A process for the production of 2-chlorobenzonitrile derivatives | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 1980-01-23 | — | — | EP | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200157043-A1 | PROCESS FOR PREPARATION OF 2,6-DICHLOROBENZONITRILE | DDT, DCUN1D4, DCUN1D2 | VCAM1 4405/4885HPGD 1642/4885TDP1 4107/4885 |
| US-11708322-B2 | Process for preparation of 2,6-dichlorobenzonitrile | DDT, DCUN1D2, DCUN1D4 | VCAM1 4406/4885HPGD 1642/4885TDP1 4094/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.