Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL29963744 | 0.71 | — | — | |
| SCHEMBL487378 | 0.69 | SOS1 (0.30) | — | |
| Lithium Ion SCHEMBL3979701 | 0.68 | — | — | |
| Iodide SCHEMBL1885520 | 0.67 | — | — | |
| Ammonia Solution, Strong SCHEMBL28924970 | 0.67 | — | — | |
| Hydrochloric Acid SCHEMBL28491334 | 0.67 | — | — | |
| SCHEMBL27839045 | 0.67 | — | — | |
| Hydrochloric Acid SCHEMBL8891874 | 0.67 | — | — | |
| SCHEMBL6049394 | 0.65 | — | — | |
| SCHEMBL301535 | 0.65 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3880685-B1 | INHIBITORS OF ARG1 AND/OR ARG2 | ARCUS BIOSCIENCES INC (US) | 2025-06-18 | — | — | EP | disclosed |
| US-12226425-B2 | Inhibitors of ARG1 and/or ARG2 | ARCUS BIOSCIENCES, INC. (US) | 2025-02-18 | — | — | US | disclosed |
| US-20230247994-A1 | HETEROCYCLENE DERIVATIVES AS PEST CONTROL AGENTS | BAYER AKTIENGESELLSCHAFT (DE) | 2023-08-10 | — | — | US | disclosed |
| EP-4175961-A1 | HETEROCYCLENE DERIVATIVES AS PEST CONTROL AGENTS | Bayer Aktiengesellschaft (DE) | 2023-05-10 | — | — | EP | disclosed |
| US-20220016143-A1 | INHIBITORS OF ARG1 AND/OR ARG2 | ARCUS BIOSCIENCES, INC. | 2022-01-20 | — | — | US | disclosed |
| WO-2022002818-A1 | HETEROCYCLENE DERIVATIVES AS PEST CONTROL AGENTS | BAYER AKTIENGESELLSCHAFT (DE) | 2022-01-06 | — | — | WO | disclosed |
| EP-3880685-A2 | INHIBITORS OF ARG1 AND/OR ARG2 | Arcus Biosciences, Inc. (US) | 2021-09-22 | — | — | EP | disclosed |
| WO-2020102646-A2 | INHIBITORS OF ARG1 AND/OR ARG2 | ARCUS BIOSCIENCES, INC. (US) | 2020-05-22 | — | — | WO | disclosed |