SCHEMBL21962422

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL22012111	0.91	ESR2 (0.51)	NR1H2ESR2ADORA1BRD4CREBBP
	SCHEMBL4183295	0.88	ESR2 (0.50)	NR1H2ESR2ADORA1BRD4CREBBP
	SCHEMBL21962254	0.85	ESR2 (0.47)	NR1H2ESR2ADORA1BRD4CREBBP
	SCHEMBL22012113	0.85	NR1H2 (0.45)	NR1H2ESR2ADORA1BRD4CREBBP
	SCHEMBL14876121	0.83	NR1H2 (0.60)	NR1H2ESR2ADORA1BRD4CREBBP
	SCHEMBL21962187	0.82	ESR2 (0.44)	NR1H2ESR2ADORA1BRD4CREBBP
	SCHEMBL6421569	0.81	ESR2 (0.55)	NR1H2ESR2ADORA1BRD4CREBBP
	SCHEMBL6421478	0.81	NR1H2 (0.54)	NR1H2ESR2ADORA1BRD4CREBBP
	SCHEMBL1017283	0.80	ESR2 (0.54)	NR1H2ESR2ADORA1BRD4CREBBP
	SCHEMBL22369230	0.80	ESR2 (0.54)	NR1H2ESR2ADORA1BRD4CREBBP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.