Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRD5A2 | P31213 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | CES2 | O00748 | 1/20 | 0.40 |
| ▸ | VNN1 | O95497 | 6/20 | 0.40 |
| ▸ | CNR2 | P34972 | 2/20 | 0.39 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.39 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.39 |
| ▸ | KCNE1 | P15382 | 1/20 | 0.39 |
| ▸ | KCNQ1 | P51787 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21962791 | 0.93 | MEN1 (0.42) | SRD5A2MEN1KMT2AALDH1A1CYP1A2 | |
| SCHEMBL21962451 | 0.91 | MEN1 (0.41) | SRD5A2MEN1KMT2AALDH1A1CYP1A2 | |
| SCHEMBL21962579 | 0.81 | SRD5A2 (0.43) | SRD5A2MEN1KMT2AALDH1A1CYP1A2 | |
| SCHEMBL21962395 | 0.81 | SRD5A2 (0.43) | SRD5A2MEN1KMT2AALDH1A1CYP1A2 | |
| SCHEMBL22019136 | 0.81 | SRD5A2 (0.43) | SRD5A2MEN1KMT2AALDH1A1CYP1A2 | |
| SCHEMBL21962600 | 0.81 | HPGD (0.42) | SRD5A2MEN1KMT2AALDH1A1CYP1A2 | |
| SCHEMBL21962547 | 0.81 | HDAC3 (0.44) | SRD5A2MEN1KMT2AALDH1A1CYP1A2 | |
| SCHEMBL22020545 | 0.81 | HDAC3 (0.44) | SRD5A2MEN1KMT2AALDH1A1CYP1A2 | |
| SCHEMBL21962651 | 0.80 | VNN1 (0.43) | SRD5A2MEN1KMT2AALDH1A1CYP1A2 | |
| SCHEMBL21962779 | 0.79 | MLYCD (0.49) | SRD5A2MEN1KMT2AALDH1A1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020102575-A1 | HETEROCYCLIC AMINOTHIAZOLES AND USES THEREOF | INCEPTION IBD, INC. (US) | 2020-05-22 | — | — | WO | claimed |
| WO-2020102575-A1 | HETEROCYCLIC AMINOTHIAZOLES AND USES THEREOF | INCEPTION IBD, INC. (US) | 2020-05-22 | — | — | WO | disclosed |
| WO-2020102575-A1 | HETEROCYCLIC AMINOTHIAZOLES AND USES THEREOF | INCEPTION IBD, INC. (US) | 2020-05-22 | — | — | WO | disclosed |