Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VNN1 | O95497 | 7/20 | 0.38 |
| ▸ | MLYCD | O95822 | 1/20 | 0.36 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.36 |
| ▸ | KRAS | P01116 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.35 |
| ▸ | KDM4A | O75164 | 1/20 | 0.35 |
| ▸ | KDM4B | O94953 | 1/20 | 0.35 |
| ▸ | KDM5C | P41229 | 1/20 | 0.35 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.35 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.35 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | PDE4A | P27815 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | CHKA | P35790 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21962808 | 0.84 | VNN1 (0.39) | VNN1MLYCDLOXL2KRASKDM4A | |
| SCHEMBL21962451 | 0.84 | MEN1 (0.41) | VNN1KCNH2ALDH1A1 | |
| SCHEMBL22020529 | 0.83 | VNN1 (0.36) | VNN1MLYCDALDH1A1HTT | |
| SCHEMBL21962628 | 0.82 | MLYCD (0.42) | VNN1MLYCDLOXL2KDM4AKDM4B | |
| SCHEMBL22019134 | 0.82 | MLYCD (0.42) | VNN1MLYCDLOXL2KDM4AKDM4B | |
| SCHEMBL22019310 | 0.82 | VNN1 (0.38) | VNN1MLYCDLOXL2KDM4AKDM4B | |
| SCHEMBL22019135 | 0.82 | VNN1 (0.38) | VNN1MLYCDLOXL2KDM4AKDM4B | |
| SCHEMBL21962836 | 0.81 | RAF1 (0.44) | VNN1MLYCDLOXL2KDM4AKDM4B | |
| SCHEMBL21962640 | 0.81 | VNN1 (0.38) | VNN1MLYCDLOXL2KRASKDM4A | |
| SCHEMBL21962795 | 0.81 | MLYCD (0.42) | VNN1MLYCDKDM4AKDM4BKDM5C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020102575-A1 | HETEROCYCLIC AMINOTHIAZOLES AND USES THEREOF | INCEPTION IBD, INC. (US) | 2020-05-22 | — | — | WO | claimed |
| WO-2020102575-A1 | HETEROCYCLIC AMINOTHIAZOLES AND USES THEREOF | INCEPTION IBD, INC. (US) | 2020-05-22 | — | — | WO | disclosed |