Sugi Predict

Sugi Predict / Compounds / SCHEMBL2196275

SCHEMBL2196275

SCHEMBL2196275

O=C1CC/C=C/CCCCCCCCCCC1

nearest known ligand 0.58

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
▸ TRIM24 O15164 2/20 0.58
▸ TRIM33 Q9UPN9 2/20 0.58
▸ ALDH1A1 P00352 2/20 0.58
▸ HDAC3 O15379 1/20 0.33
▸ HDAC4 P56524 1/20 0.33
▸ HDAC1 Q13547 1/20 0.33
▸ HDAC7 Q8WUI4 1/20 0.33
▸ HDAC2 Q92769 1/20 0.33
▸ HDAC10 Q969S8 1/20 0.33
▸ HDAC11 Q96DB2 1/20 0.33
▸ HDAC8 Q9BY41 1/20 0.33
▸ HDAC6 Q9UBN7 1/20 0.33
▸ HDAC9 Q9UKV0 1/20 0.33
▸ HDAC5 Q9UQL6 1/20 0.33
▸ CXCR3 P49682 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4326616 1.00 TRIM24 (0.58) TRIM24TRIM33ALDH1A1HDAC3HDAC4
SCHEMBL4584382 1.00 TRIM24 (0.58) TRIM24TRIM33ALDH1A1HDAC3HDAC4
SCHEMBL4320869 1.00 TRIM24 (0.58) TRIM24TRIM33ALDH1A1HDAC3HDAC4
SCHEMBL4326621 1.00 TRIM24 (0.58) TRIM24TRIM33ALDH1A1HDAC3HDAC4
SCHEMBL2196280 1.00 TRIM24 (0.58) TRIM24TRIM33ALDH1A1HDAC3HDAC4
SCHEMBL4326629 1.00 TRIM24 (0.58) TRIM24TRIM33ALDH1A1HDAC3HDAC4
SCHEMBL236422 1.00 TRIM24 (0.58) TRIM24TRIM33ALDH1A1HDAC3HDAC4
SCHEMBL4326613 1.00 TRIM24 (0.58) TRIM24TRIM33ALDH1A1HDAC3HDAC4
SCHEMBL4584380 1.00 TRIM24 (0.58) TRIM24TRIM33ALDH1A1HDAC3HDAC4
SCHEMBL4320871 1.00 TRIM24 (0.58) TRIM24TRIM33ALDH1A1HDAC3HDAC4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1264594-B1 Melanin production inhibitors and skincare products containing such inhibitors TAKASAGO PERFUMERY CO LTD (JP) 2006-11-29 — — EP claimed
US-6759557-B2 MACROCYCLIC HYDROCARBON RINGS WITH HYDROXYL AND/OR KETONE FUNCTIONALITIES, SUCH AS CYCLOTETRADECANONE OR 2-HYDROXYCYCLOHEXADECANONE, OPTIONALLY WITH SKIN WHITENING AGENTS AND/OR UV ABSORBERS TAKASAGO INTERNATIONAL CORPORATION (JP) 2004-07-06 — — US claimed
US-20030049213-A1 Melanin production inhibitors and skincare products containing such inhibitors TAKASAGO INTERNATIONAL CORPORATION (JP) 2003-03-13 — — US claimed
EP-1264594-A2 Melanin production inhibitors and skincare products containing such inhibitors Takasago International Corporation (JP) 2002-12-11 — — EP claimed
US-20160000691-A1 Topical Compositions And Methods For Whitening Skin ELC MAN LLC (US) 2016-01-07 — — US disclosed
EP-2133102-B1 Odor reducers SYMRISE AG (DE) 2014-12-03 — — EP disclosed
US-8852565-B2 Odour-reducing substances SYMRISE AG (DE) 2014-10-07 — — US disclosed
US-8539631-B2 Roller for providing benefits to fabric THE PROCTER & GAMBLE COMPANY (US) 2013-09-24 — — US disclosed
US-20110171288-A1 TOPICAL COMPOSITIONS AND METHODS FOR WHITENING SKIN MOHAMMADI FATEMEH 2011-07-14 — — US disclosed
WO-2010094546-A2 ANTIPERSPIRANT COMPOSITIONS UNILEVER PLC (GB) 2010-08-26 — — WO disclosed
EP-2133102-A1 Odor reducers Symrise GmbH & Co. KG (DE) 2009-12-16 — — EP disclosed
US-7615526-B2 Furanoid and pyranoid C14-C18- oxabicycloalkanones as odoriferous and/or aroma substances SYMRISE GMBH & CO. KG (DE) 2009-11-10 — — US disclosed
WO-2006010087-A1 ROLLER FOR PROVIDING BENEFITS TO FABRIC THE PROCTER & GAMBLE COMPANY (US) 2006-01-26 — — WO disclosed
WO-2006003053-A1 USE OF 3-MERCAPTO-3-METHYL-HEXAN-1-OL FUR USE AS MALODOR STANDARD SYMRISE GMBH & CO. KG (DE) 2006-01-12 — — WO disclosed
US-20060005333-A1 Roller for providing benefits to fabric PROCTER & GAMBLE COMPANY, THE 2006-01-12 — — US disclosed
US-20050271608-A1 Skin whitening compositions based on hydroxyaryl alkyl ketones and their isosteric derivatives GUPTA SHYAM K 2005-12-08 — — US disclosed
WO-2005063670-A1 USE OF (Z)-7-CYCLOHEXADECENE-1-ONE AS A PERFUME SYMRISE GMBH & CO. KG (DE) 2005-07-14 — — WO disclosed
US-6759557-B2 MACROCYCLIC HYDROCARBON RINGS WITH HYDROXYL AND/OR KETONE FUNCTIONALITIES, SUCH AS CYCLOTETRADECANONE OR 2-HYDROXYCYCLOHEXADECANONE, OPTIONALLY WITH SKIN WHITENING AGENTS AND/OR UV ABSORBERS TAKASAGO INTERNATIONAL CORPORATION (JP) 2004-07-06 — — US disclosed
US-20030049213-A1 Melanin production inhibitors and skincare products containing such inhibitors TAKASAGO INTERNATIONAL CORPORATION (JP) 2003-03-13 — — US disclosed
EP-1264594-A2 Melanin production inhibitors and skincare products containing such inhibitors Takasago International Corporation (JP) 2002-12-11 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160000691-A1 Topical Compositions And Methods For Whitening Skin CUTA, COL14A1, KRT18 TRIM24 4075/4885TRIM33 3413/4885ALDH1A1 863/4885
US-20030049213-A1 Melanin production inhibitors and skincare products containing such inhibitors TYR, AOC3, DOHH TRIM24 444/4885TRIM33 4685/4885ALDH1A1 322/4885
US-20110171288-A1 TOPICAL COMPOSITIONS AND METHODS FOR WHITENING SKIN CUTA, COL14A1, KRT18 TRIM24 4075/4885TRIM33 3413/4885ALDH1A1 863/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.