Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.51 |
| ▸ | FDFT1 | P37268 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.47 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.47 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.47 |
| ▸ | MAOB | P27338 | 7/20 | 0.46 |
| ▸ | MAOA | P21397 | 4/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10272647 | 0.86 | MRGPRX4 (0.64) | MRGPRX4FDFT1LMNACYP1A2PTGS1 | |
| SCHEMBL17468456 | 0.85 | TP53 (0.52) | MRGPRX4FDFT1LMNACYP1A2PTGS1 | |
| SCHEMBL11047683 | 0.82 | GRIN1 (0.50) | MRGPRX4FDFT1LMNACYP1A2PTGS1 | |
| SCHEMBL5249481 | 0.81 | HRH3 (0.60) | MRGPRX4FDFT1LMNACYP1A2PTGS1 | |
| SCHEMBL16969436 | 0.81 | ESR2 (0.57) | MRGPRX4FDFT1LMNACYP1A2PTGS1 | |
| SCHEMBL28601145 | 0.79 | LMNA (0.47) | LMNACYP1A2PTGS1SLC6A2CYP2C19 | |
| SCHEMBL12523729 | 0.79 | MRGPRX4 (0.57) | MRGPRX4FDFT1LMNACYP1A2PTGS1 | |
| SCHEMBL12525375 | 0.79 | MRGPRX4 (0.57) | MRGPRX4FDFT1LMNACYP1A2PTGS1 | |
| SCHEMBL20930997 | 0.79 | MAOB (0.62) | MRGPRX4LMNACYP1A2PTGS1SLC6A2 | |
| SCHEMBL7369689 | 0.79 | MRGPRX4 (0.60) | MRGPRX4FDFT1LMNACYP1A2PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3643703-A1 | EP300/CREBBP INHIBITOR | Daiichi Sankyo Co., Ltd. (JP) | 2020-04-29 | — | — | EP | disclosed |