Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | MAPK13 | O15264 | 9/20 | 0.46 |
| ▸ | MAPK12 | P53778 | 9/20 | 0.46 |
| ▸ | MAPK11 | Q15759 | 9/20 | 0.46 |
| ▸ | MAPK14 | Q16539 | 9/20 | 0.46 |
| ▸ | EGFR | P00533 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2196461 | 1.00 | MAPK1 (0.47) | MAPK1MAPK13MAPK12MAPK11MAPK14 | |
| SCHEMBL6817360 | 0.90 | MAPK1 (0.49) | MAPK1MAPK13MAPK12MAPK11MAPK14 | |
| SCHEMBL6817365 | 0.90 | MAPK1 (0.49) | MAPK1MAPK13MAPK12MAPK11MAPK14 | |
| SCHEMBL2198530 | 0.89 | MAPK13 (0.52) | MAPK13MAPK12MAPK11MAPK14SMN1; SMN2 | |
| SCHEMBL2198552 | 0.87 | MAPK13 (0.57) | MAPK13MAPK12MAPK11MAPK14EGFR | |
| SCHEMBL2199221 | 0.86 | MAPK13 (0.47) | MAPK13MAPK12MAPK11MAPK14EGFR | |
| SCHEMBL2199317 | 0.86 | MAPK13 (0.56) | MAPK13MAPK12MAPK11MAPK14SMN1; SMN2 | |
| SCHEMBL6817261 | 0.85 | MAPK1 (0.54) | MAPK1MAPK13MAPK12MAPK11MAPK14 | |
| SCHEMBL6817260 | 0.85 | MAPK1 (0.54) | MAPK1MAPK13MAPK12MAPK11MAPK14 | |
| SCHEMBL2200351 | 0.84 | MAPK14 (0.66) | MAPK13MAPK12MAPK11MAPK14EGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060166990-A1 | Novel aminobenzophenone compounds | LEO PHARMA A/S (DK) | 2006-07-27 | — | — | US | claimed |
| US-7977387-B2 | Aminobenzophenone compounds | LEO PHARMA A/S (DK) | 2011-07-12 | — | — | US | disclosed |
| US-20060166990-A1 | Novel aminobenzophenone compounds | LEO PHARMA A/S (DK) | 2006-07-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060166990-A1 | Novel aminobenzophenone compounds | NFKBIA, UACA, ALDH7A1 | MAPK1 523/4885MAPK13 1063/4885MAPK12 955/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.