Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 3/20 | 0.39 |
| ▸ | CA2 | P00918 | 3/20 | 0.39 |
| ▸ | CA4 | P22748 | 2/20 | 0.39 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
| ▸ | CA6 | P23280 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.32 |
| ▸ | TLR4 | O00206 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.30 |
| ▸ | MT-CO2 | P00403 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2194767 | 1.00 | KMT2A (0.42) | KMT2ACA1CA2CA4MCL1 | |
| SCHEMBL2196527 | 1.00 | KMT2A (0.42) | KMT2ACA1CA2CA4MCL1 | |
| SCHEMBL15457462 | 1.00 | KMT2A (0.42) | KMT2ACA1CA2CA4MCL1 | |
| SCHEMBL2194743 | 1.00 | KMT2A (0.42) | KMT2ACA1CA2CA4MCL1 | |
| SCHEMBL2193711 | 1.00 | KMT2A (0.42) | KMT2ACA1CA2CA4MCL1 | |
| SCHEMBL2194749 | 1.00 | KMT2A (0.42) | KMT2ACA1CA2CA4MCL1 | |
| SCHEMBL2201609 | 1.00 | KMT2A (0.42) | KMT2ACA1CA2CA4MCL1 | |
| SCHEMBL2194769 | 1.00 | KMT2A (0.42) | KMT2ACA1CA2CA4MCL1 | |
| SCHEMBL2193109 | 1.00 | KMT2A (0.42) | KMT2ACA1CA2CA4MCL1 | |
| SCHEMBL6055714 | 1.00 | KMT2A (0.42) | KMT2ACA1CA2CA4MCL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1264594-B1 | Melanin production inhibitors and skincare products containing such inhibitors | TAKASAGO PERFUMERY CO LTD (JP) | 2006-11-29 | — | — | EP | claimed |
| US-6759557-B2 | MACROCYCLIC HYDROCARBON RINGS WITH HYDROXYL AND/OR KETONE FUNCTIONALITIES, SUCH AS CYCLOTETRADECANONE OR 2-HYDROXYCYCLOHEXADECANONE, OPTIONALLY WITH SKIN WHITENING AGENTS AND/OR UV ABSORBERS | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2004-07-06 | — | — | US | claimed |
| US-20030049213-A1 | Melanin production inhibitors and skincare products containing such inhibitors | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2003-03-13 | — | — | US | claimed |
| EP-1264594-A2 | Melanin production inhibitors and skincare products containing such inhibitors | Takasago International Corporation (JP) | 2002-12-11 | — | — | EP | claimed |
| US-20160000691-A1 | Topical Compositions And Methods For Whitening Skin | ELC MAN LLC (US) | 2016-01-07 | — | — | US | disclosed |
| US-20110171288-A1 | TOPICAL COMPOSITIONS AND METHODS FOR WHITENING SKIN | MOHAMMADI FATEMEH | 2011-07-14 | — | — | US | disclosed |
| EP-2254546-A2 | TOPICAL COMPOSITIONS AND METHODS FOR WHITENING SKIN | ELC Management LLC (US) | 2010-12-01 | — | — | EP | disclosed |
| WO-2009105294-A2 | TOPICAL COMPOSITIONS AND METHODS FOR WHITENING SKIN | ELC MANAGEMENT LLC (US) | 2009-08-27 | — | — | WO | disclosed |
| EP-1264594-B1 | Melanin production inhibitors and skincare products containing such inhibitors | TAKASAGO PERFUMERY CO LTD (JP) | 2006-11-29 | — | — | EP | disclosed |
| US-6759557-B2 | MACROCYCLIC HYDROCARBON RINGS WITH HYDROXYL AND/OR KETONE FUNCTIONALITIES, SUCH AS CYCLOTETRADECANONE OR 2-HYDROXYCYCLOHEXADECANONE, OPTIONALLY WITH SKIN WHITENING AGENTS AND/OR UV ABSORBERS | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2004-07-06 | — | — | US | disclosed |
| US-20030049213-A1 | Melanin production inhibitors and skincare products containing such inhibitors | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2003-03-13 | — | — | US | disclosed |
| EP-1264594-A2 | Melanin production inhibitors and skincare products containing such inhibitors | Takasago International Corporation (JP) | 2002-12-11 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160000691-A1 | Topical Compositions And Methods For Whitening Skin | CUTA, COL14A1, KRT18 | KMT2A 3643/4885CA1 3406/4885CA2 1629/4885 |
| US-20030049213-A1 | Melanin production inhibitors and skincare products containing such inhibitors | TYR, AOC3, DOHH | KMT2A 1713/4885CA1 4605/4885CA2 3711/4885 |
| US-20110171288-A1 | TOPICAL COMPOSITIONS AND METHODS FOR WHITENING SKIN | CUTA, COL14A1, KRT18 | KMT2A 3643/4885CA1 3406/4885CA2 1629/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.