Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2B | P29275 | 4/20 | 0.46 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.46 |
| ▸ | ESR1 | P03372 | 1/20 | 0.41 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | HCAR1 | Q9BXC0 | 1/20 | 0.37 |
| ▸ | BACE1 | P56817 | 1/20 | 0.36 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22662016 | 0.99 | ADORA2B (0.45) | ADORA2BADORA1ESR1ESR2MAPK1 | |
| SCHEMBL22662015 | 0.97 | ADORA2B (0.44) | ADORA2BADORA1ESR1ESR2MAPK1 | |
| SCHEMBL22662205 | 0.96 | ADORA2B (0.43) | ADORA2BADORA1ESR1ESR2MAPK1 | |
| SCHEMBL22357652 | 0.95 | ADORA2B (0.42) | ADORA2BADORA1ESR1ESR2MAPK1 | |
| SCHEMBL22662003 | 0.94 | ADORA2B (0.42) | ADORA2BADORA1ESR1ESR2MAPK1 | |
| SCHEMBL22662014 | 0.93 | ESR1 (0.43) | ADORA2BADORA1ESR1ESR2MAPK1 | |
| SCHEMBL22662009 | 0.93 | ESR1 (0.42) | ADORA2BADORA1ESR1ESR2MAPK1 | |
| SCHEMBL22662010 | 0.92 | ESR1 (0.44) | ADORA2BADORA1ESR1ESR2MAPK1 | |
| SCHEMBL22662005 | 0.92 | MAPK1 (0.42) | ADORA2BADORA1ESR1ESR2MAPK1 | |
| SCHEMBL22662006 | 0.91 | ESR1 (0.41) | ADORA2BADORA1ESR1ESR2MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200144512-A1 | ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES | UNIVERSAL DISPLAY CORPORATION (US) | 2020-05-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200144512-A1 | ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES | GDA, SOD1, GALC | ADORA2B 1129/4885ADORA1 1375/4885ESR1 487/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.