SCHEMBL21966652

SCHEMBL21966652

c1ccc(N(c2ccc3ccccc3c2)c2ccc3c(c2)sc2ccc(N(c4ccccc4)c4ccccc4)cc23)cc1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 3/20 0.36
ALDH1A1 P00352 2/20 0.36
SMN1; SMN2 Q16637 2/20 0.36
HPGD P15428 1/20 0.36
RAB9A P51151 1/20 0.36
CYP1A2 P05177 2/20 0.33
KDM4E B2RXH2 1/20 0.33
CYP3A4 P08684 1/20 0.33
CYP2D6 P10635 1/20 0.33
CYP2C9 P11712 1/20 0.33
CYP2C19 P33261 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
GPR3 P46089 1/20 0.33
PTPN7 P35236 1/20 0.33
DUSP3 P51452 1/20 0.33
PTPN12 Q05209 1/20 0.33
PTPN22 Q9Y2R2 1/20 0.33
INSR P06213 1/20 0.30
IGF1R P08069 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19429033 1.00 MAPT (0.36) MAPTALDH1A1SMN1; SMN2HPGDRAB9A
SCHEMBL18927735 1.00 MAPT (0.36) MAPTALDH1A1SMN1; SMN2HPGDRAB9A
SCHEMBL23515783 1.00 MAPT (0.36) MAPTALDH1A1SMN1; SMN2HPGDRAB9A
SCHEMBL20201279 0.97 MAPT (0.41) MAPTALDH1A1SMN1; SMN2HPGDRAB9A
SCHEMBL21968669 0.97 MAPT (0.41) MAPTALDH1A1SMN1; SMN2HPGDRAB9A
SCHEMBL19429064 0.97 MAPT (0.41) MAPTALDH1A1SMN1; SMN2HPGDRAB9A
SCHEMBL19429057 0.97 MAPT (0.41) MAPTALDH1A1SMN1; SMN2HPGDRAB9A
SCHEMBL24154575 0.94 MAPT (0.42) MAPTALDH1A1SMN1; SMN2HPGDRAB9A
SCHEMBL12117288 0.94 ALDH1A1 (0.35) MAPTALDH1A1SMN1; SMN2HPGDRAB9A
SCHEMBL17740705 0.94 ALDH1A1 (0.37) MAPTALDH1A1SMN1; SMN2HPGDRAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20200176685-A1 ORGANIC OPTOELECTRONIC DEVICE AND DISPLAY DEVICE SAMSUNG SDI CO., LTD. (KR) 2020-06-04 US disclosed
US-20200144508-A1 ORGANIC OPTOELECTRONIC DEVICE AND DISPLAY DEVICE SAMSUNG SDI CO., LTD. (KR) 2020-05-07 US disclosed
US-20200144510-A1 ORGANIC OPTOELECTRONIC DEVICE AND DISPLAY DEVICE SAMSUNG SDI CO., LTD. (KR) 2020-05-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200144508-A1 ORGANIC OPTOELECTRONIC DEVICE AND DISPLAY DEVICE OCIAD1, OCIAD2, OR10J3 MAPT 2375/4885ALDH1A1 49/4885SMN1; SMN2 4676/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.