SCHEMBL17740705

SCHEMBL17740705

c1ccc(N(c2ccc3ccccc3c2)c2ccc3c(c2)sc2cc(N(c4ccccc4)c4ccc5ccccc5c4)ccc23)cc1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.37
MAPT P10636 3/20 0.37
L3MBTL1 Q9Y468 3/20 0.37
KDM4E B2RXH2 2/20 0.37
CYP1A2 P05177 2/20 0.37
CYP3A4 P08684 1/20 0.37
CYP2D6 P10635 1/20 0.37
CYP2C9 P11712 1/20 0.37
CYP2C19 P33261 1/20 0.37
TDP1 Q9NUW8 1/20 0.37
SMN1; SMN2 Q16637 2/20 0.36
HPGD P15428 1/20 0.36
RAB9A P51151 1/20 0.36
GPR3 P46089 1/20 0.33
INSR P06213 1/20 0.33
IGF1R P08069 1/20 0.33
MEN1 O00255 1/20 0.33
CRHBP P24387 1/20 0.33
KMT2A Q03164 1/20 0.33
ATM Q13315 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21966652 0.94 MAPT (0.36) ALDH1A1MAPTL3MBTL1KDM4ECYP1A2
SCHEMBL19429033 0.94 MAPT (0.36) ALDH1A1MAPTL3MBTL1KDM4ECYP1A2
SCHEMBL18927735 0.94 MAPT (0.36) ALDH1A1MAPTL3MBTL1KDM4ECYP1A2
SCHEMBL23515783 0.94 MAPT (0.36) ALDH1A1MAPTL3MBTL1KDM4ECYP1A2
SCHEMBL17740646 0.93 ACMSD (0.37) ALDH1A1MAPTL3MBTL1KDM4ECYP1A2
SCHEMBL17740626 0.93 LIMK1 (0.37) ALDH1A1MAPTL3MBTL1KDM4ECYP1A2
SCHEMBL19429057 0.91 MAPT (0.41) ALDH1A1MAPTL3MBTL1KDM4ECYP1A2
SCHEMBL21968669 0.91 MAPT (0.41) ALDH1A1MAPTL3MBTL1KDM4ECYP1A2
SCHEMBL20201279 0.91 MAPT (0.41) ALDH1A1MAPTL3MBTL1KDM4ECYP1A2
SCHEMBL19429064 0.91 MAPT (0.41) ALDH1A1MAPTL3MBTL1KDM4ECYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11812657-B2 Organic electric element DUK SAN NEOLUX CO., LTD. 2023-11-07 US disclosed
US-11812657-B2 Organic electric element DUK SAN NEOLUX CO., LTD. 2023-11-07 US disclosed
US-20230276699-A1 Organic Electric Element DUK SAN NEOLUX CO LTD (KR) 2023-08-31 US disclosed
US-20230276699-A1 Organic Electric Element DUK SAN NEOLUX CO LTD (KR) 2023-08-31 US disclosed
US-20220209127-A1 ORGANIC ELECTRIC ELEMENT DUK SAN NEOLUX CO., LTD (KR) 2022-06-30 US disclosed
US-20160211459-A1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2016-07-21 US disclosed
US-20160211459-A1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2016-07-21 US disclosed
WO-2016072691-A1 ORGANIC ELECTRONIC DEVICE AND DISPLAY DEVICE USING COMPOSITION FOR ORGANIC ELECTRONIC DEVICE 덕산네오룩스 주식회사 2016-05-12 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230276699-A1 Organic Electric Element EPCAM, ESR1, SOD1 ALDH1A1 3397/4885MAPT 1628/4885L3MBTL1 1123/4885
US-20220209127-A1 ORGANIC ELECTRIC ELEMENT EPCAM, ESR1, SOD1 ALDH1A1 3397/4885MAPT 1628/4885L3MBTL1 1123/4885
US-11812657-B2 Organic electric element EPCAM, ESR1, SOD1 ALDH1A1 3397/4885MAPT 1628/4885L3MBTL1 1123/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.