SCHEMBL21969746

SCHEMBL21969746

Cc1ccc(C)c2c1C(=O)c1nonc1C2=O

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NQO1 P15559 1/20 0.44
POR P16435 1/20 0.44
TDP1 Q9NUW8 1/20 0.37
NSD2 O96028 2/20 0.37
TDP2 O95551 1/20 0.37
HSP90AA1 P07900 1/20 0.37
PAX8 Q06710 1/20 0.37
CA1 P00915 5/20 0.36
CA2 P00918 5/20 0.36
CA12 O43570 4/20 0.36
CA9 Q16790 4/20 0.36
TOP2A P11388 1/20 0.35
USP8 P40818 1/20 0.35
L3MBTL1 Q9Y468 4/20 0.33
ALDH1A1 P00352 3/20 0.33
MAPK1 P28482 2/20 0.33
NPC1 O15118 2/20 0.33
RAB9A P51151 2/20 0.33
SMN1; SMN2 Q16637 2/20 0.33
BRD4 O60885 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21969744 0.78 TDP1 (0.33) TDP1
SCHEMBL21970024 0.76
SCHEMBL19104645 0.75 USP8 (0.34) TDP1USP8L3MBTL1MAPK1
SCHEMBL21969745 0.74 CA12 (0.35) TDP1CA1CA2CA12CA9
SCHEMBL6152288 0.74 NQO1 (0.52) NQO1PORTDP1NSD2TDP2
SCHEMBL21970048 0.73 MEN1 (0.39) NQO1PORNSD2TDP2HSP90AA1
SCHEMBL7984632 0.68 USP8 (0.60) TDP1CA1CA2CA9USP8
SCHEMBL7918737 0.67 MEN1 (0.52) TDP1TDP2CA1CA2CA12
SCHEMBL13051339 0.65 NSD2 (0.48) NQO1PORNSD2TDP2HSP90AA1
SCHEMBL11884841 0.65 RPS6KB1 (0.46) ALDH1A1NPC1RAB9ASMN1; SMN2TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11299581-B2 Conjugated polymer and application thereof RAYNERGY TEK INC. (TW) 2022-04-12 US disclosed
US-20210171705-A1 CONJUGATED POLYMER MATERIAL AND ORGANIC PHOTOVOLTAIC DEVICE USING THE SAME Raynergy Tek Incorporation (TW) 2021-06-10 US disclosed
US-20200140605-A1 CONJUGATED POLYMER AND APPLICATION THEREOF RAYNERGY TEK INC. (TW) 2020-05-07 US disclosed