Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RPS6KB1 | P23443 | 8/20 | 0.46 |
| ▸ | GSK3B | P49841 | 5/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | ROCK1 | Q13464 | 5/20 | 0.43 |
| ▸ | PRKACA | P17612 | 4/20 | 0.43 |
| ▸ | RPS6KA5 | O75582 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 3/20 | 0.41 |
| ▸ | NOS3 | P29474 | 1/20 | 0.39 |
| ▸ | NOS1 | P29475 | 1/20 | 0.39 |
| ▸ | NOS2 | P35228 | 1/20 | 0.39 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.39 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14364599 | 0.72 | SMN1; SMN2 (0.61) | RPS6KB1GSK3BSMN1; SMN2TP53TSHR | |
| SCHEMBL28366110 | 0.71 | RECQL (0.54) | RPS6KB1GSK3BSMN1; SMN2TSHRRAB9A | |
| SCHEMBL543895 | 0.70 | LMNA (0.54) | RPS6KB1GSK3BSMN1; SMN2TP53TSHR | |
| SCHEMBL17861269 | 0.69 | RAB9A (0.44) | RPS6KB1GSK3BSMN1; SMN2TP53TSHR | |
| SCHEMBL29088212 | 0.69 | RECQL (0.52) | RPS6KB1GSK3BSMN1; SMN2TSHRRAB9A | |
| SCHEMBL17844127 | 0.67 | NOTUM (0.44) | RPS6KB1GSK3BSMN1; SMN2TP53TSHR | |
| SCHEMBL21969746 | 0.65 | NQO1 (0.44) | SMN1; SMN2TSHRNPC1RAB9AALDH1A1 | |
| SCHEMBL658209 | 0.65 | MEN1 (0.44) | RPS6KB1GSK3BSMN1; SMN2TP53NPC1 | |
| SCHEMBL4021982 | 0.65 | ACHE (0.57) | TSHRALDH1A1NOS3NOS1NOS2 | |
| SCHEMBL31686421 | 0.62 | RECQL (0.58) | RPS6KB1GSK3BSMN1; SMN2TP53TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3711609-A | CERTAIN FURAZAN DERIVATIVES IN THERAPEUTIC COMPOSITIONS AND METHODS | CIBA GEIGY CORP | 1973-01-16 | — | — | US | disclosed |