Phosphonic Acid

Phosphonic Acid

SCHEMBL2197002

CC(C)(C)c1ccc(-c2cccc(-c3ccccc3)c2-c2ccc(C(C)(C)C)cc2C(C)(C)C)c(C(C)(C)C)c1.O=[PH](O)O

nearest known ligand 0.41

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 1/20 0.41
ALDH1A1 P00352 1/20 0.41
PLA2G1B P04054 1/20 0.41
NFKB1 P19838 1/20 0.41
CASP3 P42574 1/20 0.41
RAB9A P51151 1/20 0.41
NFKB2 Q00653 1/20 0.41
RELA Q04206 1/20 0.41
SENP8 Q96LD8 1/20 0.41
SENP7 Q9BQF6 1/20 0.41
SENP6 Q9GZR1 1/20 0.41
L3MBTL1 Q9Y468 1/20 0.41
ATG4B Q9Y4P1 1/20 0.41
PTPN5 P54829 1/20 0.38
RXRA P19793 2/20 0.37
RXRB P28702 2/20 0.37
GPR84 Q9NQS5 1/20 0.35
CNR1 P21554 2/20 0.34
CNR2 P34972 2/20 0.34
PLK1 P53350 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5080716 0.92 NPC1 (0.44) NPC1ALDH1A1PLA2G1BNFKB1CASP3
SCHEMBL4969211 0.91 ALDH1A1 (0.41) NPC1ALDH1A1PLA2G1BNFKB1CASP3
SCHEMBL3475180 0.89 ALDH1A1 (0.40) NPC1ALDH1A1PLA2G1BNFKB1CASP3
Phosphonic Acid SCHEMBL29555516 0.85 RXRA (0.44) NPC1ALDH1A1PLA2G1BNFKB1CASP3
Phosphonic Acid SCHEMBL455332 0.84 ALDH1A1 (0.49) NPC1ALDH1A1PLA2G1BNFKB1CASP3
Phosphonic Acid SCHEMBL2197000 0.84 ALDH1A1 (0.51) NPC1ALDH1A1PLA2G1BNFKB1CASP3
SCHEMBL30361679 0.83 NPC1 (0.37) NPC1ALDH1A1PLA2G1BNFKB1CASP3
SCHEMBL29388693 0.83 ALDH1A1 (0.47) NPC1ALDH1A1PLA2G1BNFKB1CASP3
SCHEMBL30361769 0.82 NPC1 (0.36) NPC1ALDH1A1PLA2G1BNFKB1CASP3
Phosphonic Acid SCHEMBL9417604 0.81 ALDH1A1 (0.45) NPC1ALDH1A1PLA2G1BNFKB1CASP3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7977416-B2 Mixture containing reinforcement, filler and aromatic sulfonate ASAHI KASEI CHEMICALS CORPORATION (JP) 2011-07-12 US disclosed
US-7572847-B2 Aromatic polycarbonate resin composition and production method thereof ASAHI KASEI CHEMICALS CORPORATION (JP) 2009-08-11 US disclosed
US-20080249215-A1 Aromatic polycarbonate resin composition and production method thereof ASAHI KASEI CORPORATION (JP) 2008-10-09 US disclosed
US-20070021539-A1 Aromatic polycarbonate resin composition and production method thereof ASAHI KASEI CHEMICALS CORPORATION (JP) 2007-01-25 US disclosed