Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.68 |
| ▸ | HTT | P42858 | 1/20 | 0.68 |
| ▸ | GFER | P55789 | 1/20 | 0.68 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.68 |
| ▸ | NR4A2 | P43354 | 4/20 | 0.63 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.59 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.59 |
| ▸ | SIRT2 | Q8IXJ6 | 7/20 | 0.56 |
| ▸ | SRD5A2 | P31213 | 2/20 | 0.56 |
| ▸ | SIRT3 | Q9NTG7 | 4/20 | 0.55 |
| ▸ | SIRT1 | Q96EB6 | 4/20 | 0.55 |
| ▸ | GCK | P35557 | 1/20 | 0.54 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.54 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.52 |
| ▸ | MAOB | P27338 | 1/20 | 0.52 |
| ▸ | ALKBH1 | Q13686 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30822583 | 0.98 | MEN1 (0.70) | MEN1KMT2AHTTGFERHSD17B10 | |
| SCHEMBL1201866 | 0.98 | MEN1 (0.70) | MEN1KMT2AHTTGFERHSD17B10 | |
| SCHEMBL27189439 | 0.87 | MEN1 (0.56) | MEN1KMT2AHTTGFERHSD17B10 | |
| SCHEMBL2197201 | 0.85 | PTGER1 (0.59) | MEN1KMT2AHTTGFERHSD17B10 | |
| SCHEMBL1202881 | 0.84 | SIRT2 (0.59) | MEN1KMT2AHTTGFERHSD17B10 | |
| SCHEMBL20819388 | 0.84 | MEN1 (0.54) | MEN1KMT2AHTTGFERHSD17B10 | |
| SCHEMBL20103628 | 0.83 | MEN1 (0.52) | MEN1KMT2AHTTGFERHSD17B10 | |
| SCHEMBL19251587 | 0.83 | SIRT2 (0.62) | MEN1KMT2AHTTGFERHSD17B10 | |
| SCHEMBL20103304 | 0.82 | CYP2C9 (0.57) | MEN1KMT2AHTTGFERHSD17B10 | |
| SCHEMBL8512404 | 0.82 | MAOB (0.56) | MEN1KMT2AP4HTMMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110172230-A1 | UREA COMPOUND OR SALT THEREOF | ASTELLAS PHARMA INC. (JP) | 2011-07-14 | — | — | US | disclosed |
| EP-2065369-A1 | UREA COMPOUND OR SALT THEREOF | Astellas Pharma Inc. (JP) | 2009-06-03 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110172230-A1 | UREA COMPOUND OR SALT THEREOF | FAAH, FAAH2, UTS2R | MEN1 4707/4885KMT2A 1156/4885HTT 2211/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.