SCHEMBL21972687

SCHEMBL21972687

c1ccc(-c2cccc3c(-c4ccc(C5c6c(c7ccccc7c7ccccc67)Oc6c5c5ccccc5c5ccccc65)cc4)cccc23)cc1

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.37
HSD17B10 Q99714 1/20 0.37
LIMK1 P53667 2/20 0.35
MAP4K4 O95819 1/20 0.35
CSF1R P07333 1/20 0.35
FGFR1 P11362 1/20 0.35
PDGFRA P16234 1/20 0.35
LTK P29376 1/20 0.35
KDR P35968 1/20 0.35
MAPK8 P45983 1/20 0.35
CSNK1A1 P48729 1/20 0.35
CDK5 Q00535 1/20 0.35
ACVR1 Q04771 1/20 0.35
TNK2 Q07912 1/20 0.35
AURKB Q96GD4 1/20 0.35
CLK4 Q9HAZ1 1/20 0.35
DYRK1B Q9Y463 1/20 0.35
PLG P00747 1/20 0.34
CA12 O43570 2/20 0.33
CA1 P00915 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21971029 0.95 ALDH1A1 (0.34) ALDH1A1HSD17B10KDM1AMAOBNPSR1
SCHEMBL21971736 0.95 ALDH1A1 (0.38) ALDH1A1HSD17B10LIMK1MAP4K4CSF1R
SCHEMBL21971735 0.92 CA12 (0.43) ALDH1A1HSD17B10CA12CA1CA2
SCHEMBL21971755 0.90 KDM1A (0.40) ALDH1A1HSD17B10KDM1AMAOBTP53
SCHEMBL21971028 0.90 NPSR1 (0.36) ALDH1A1HSD17B10CA12CA1CA2
SCHEMBL21971122 0.88 CA12 (0.43) ALDH1A1HSD17B10CA12CA1CA2
SCHEMBL21971640 0.86 NPSR1 (0.38) ALDH1A1HSD17B10CA12CA1CA2
SCHEMBL21971699 0.85 KDM1A (0.33) CA1CA2KDM1AMAOBMAPT
SCHEMBL21971030 0.85 ACHE (0.33) CA1CA2KDM1AMAOBMAPT
SCHEMBL21971737 0.85 MEN1 (0.35) MAP4K4CA12CA1CA2CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20200144518-A1 ORGANIC ELECTROLUMINESCENCE DEVICE AND POLYCYCLIC COMPOUND FOR ORGANIC ELECTROLUMINESCENCE DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2020-05-07 US disclosed