Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | KIF11 | P52732 | 2/20 | 0.40 |
| ▸ | WEE1 | P30291 | 4/20 | 0.39 |
| ▸ | CHEK1 | O14757 | 4/20 | 0.39 |
| ▸ | GSK3B | P49841 | 2/20 | 0.38 |
| ▸ | CDK5 | Q00535 | 2/20 | 0.38 |
| ▸ | CDK5R1 | Q15078 | 2/20 | 0.38 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.38 |
| ▸ | CDK1 | P06493 | 1/20 | 0.38 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.38 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.38 |
| ▸ | GABRP | O00591 | 1/20 | 0.38 |
| ▸ | GABRD | O14764 | 1/20 | 0.38 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.38 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.38 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.38 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29819506 | 0.84 | PARP1 (0.51) | MEN1KMT2AWEE1CHEK1GSK3B | |
| SCHEMBL17807934 | 0.84 | PARP1 (0.51) | MEN1KMT2AWEE1CHEK1GSK3B | |
| SCHEMBL24531460 | 0.84 | CCNB2 (0.44) | MEN1KMT2ANPC1WEE1CHEK1 | |
| SCHEMBL20199521 | 0.83 | PARP1 (0.50) | MEN1KMT2AWEE1CHEK1GSK3B | |
| SCHEMBL21972858 | 0.83 | BCHE (0.43) | MEN1KMT2ANPC1POLBKIF11 | |
| SCHEMBL21973496 | 0.79 | KIF11 (0.46) | MEN1KMT2ANPC1POLBKIF11 | |
| SCHEMBL20438213 | 0.77 | PARP1 (0.45) | MEN1KMT2APOLBGSK3BCDK5 | |
| SCHEMBL18858214 | 0.76 | PARP1 (0.46) | MEN1KMT2ACHEK1GSK3BCDK5 | |
| SCHEMBL3424030 | 0.75 | PARP1 (0.48) | MEN1KMT2APOLBWEE1CHEK1 | |
| SCHEMBL29520364 | 0.75 | PARP1 (0.48) | MEN1KMT2APOLBWEE1CHEK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3197982-B1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2020-05-06 | — | — | EP | disclosed |