Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 5/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | ACHE | P22303 | 2/20 | 0.42 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.40 |
| ▸ | CDK1 | P06493 | 1/20 | 0.40 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.40 |
| ▸ | GSK3B | P49841 | 1/20 | 0.40 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.40 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.40 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.40 |
| ▸ | PDK2 | Q15119 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | HPGD | P15428 | 3/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21376967 | 0.87 | KIF11 (0.45) | KIF11NPC1MEN1KMT2APOLB | |
| SCHEMBL802247 | 0.84 | AHR (0.55) | KIF11MEN1KMT2AKDM4EMAPT | |
| SCHEMBL30487042 | 0.84 | AHR (0.55) | KIF11MEN1KMT2AKDM4EMAPT | |
| SCHEMBL802805 | 0.84 | AHR (0.55) | KIF11MEN1KMT2AKDM4EMAPT | |
| SCHEMBL20199486 | 0.83 | AHR (0.53) | KIF11MEN1KMT2AKDM4EMAPT | |
| SCHEMBL17050021 | 0.81 | CDK4 (0.41) | NPC1PDK2HPGDSMN1; SMN2GABRA1 | |
| SCHEMBL802649 | 0.80 | KIF11 (0.47) | KIF11NPC1MEN1KMT2APOLB | |
| SCHEMBL21972832 | 0.79 | MEN1 (0.42) | KIF11NPC1MEN1KMT2APOLB | |
| SCHEMBL2603647 | 0.78 | AHR (0.55) | KIF11MEN1KMT2AKDM4EMAPT | |
| SCHEMBL2603653 | 0.78 | AHR (0.55) | KIF11MEN1KMT2AKDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3197982-B1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2020-05-06 | — | — | EP | disclosed |