Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.49 |
| ▸ | TYK2 | P29597 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 7/20 | 0.46 |
| ▸ | RAB9A | P51151 | 7/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | DHODH | Q02127 | 1/20 | 0.44 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.44 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | ALPL | P05186 | 1/20 | 0.43 |
| ▸ | CSF1R | P07333 | 1/20 | 0.43 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13576303 | 0.73 | HTT (0.39) | HPGDSMN1; SMN2NPC1RAB9AALDH1A1 | |
| SCHEMBL3690385 | 0.70 | HPGD (0.77) | HPGDSMN1; SMN2TYK2NPC1RAB9A | |
| SCHEMBL21993 | 0.70 | HPGD (1.00) | HPGDSMN1; SMN2TYK2NPC1RAB9A | |
| SCHEMBL27726009 | 0.69 | NPC1 (0.72) | HPGDSMN1; SMN2TYK2NPC1RAB9A | |
| SCHEMBL14420931 | 0.69 | PLK1 (0.50) | HPGDSMN1; SMN2NPC1RAB9AALDH1A1 | |
| SCHEMBL2650229 | 0.68 | POLB (0.72) | HPGDSMN1; SMN2TYK2NPC1RAB9A | |
| SCHEMBL3140037 | 0.68 | HPGD (0.64) | HPGDSMN1; SMN2TYK2NPC1RAB9A | |
| SCHEMBL2623148 | 0.68 | HPGD (0.59) | HPGDSMN1; SMN2TYK2NPC1RAB9A | |
| SCHEMBL20664916 | 0.68 | FABP4 (0.50) | HPGDALDH1A1L3MBTL1GAAMAPT | |
| SCHEMBL10252407 | 0.68 | HDAC3 (0.50) | HPGDSMN1; SMN2NPC1RAB9AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3197982-B1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2020-05-06 | — | — | EP | disclosed |