Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 3/20 | 0.45 |
| ▸ | HPGD | P15428 | 3/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | FTO | Q9C0B1 | 6/20 | 0.40 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | RORC | P51449 | 1/20 | 0.39 |
| ▸ | TTR | P02766 | 1/20 | 0.39 |
| ▸ | NAMPT | P43490 | 1/20 | 0.38 |
| ▸ | ALB | P02768 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18270247 | 0.91 | CYP3A4 (0.48) | KCNH2HPGDCYP3A4ALDH1A1TDP1 | |
| SCHEMBL25138002 | 0.89 | FTO (0.52) | KCNH2HPGDCYP3A4TDP1FTO | |
| SCHEMBL22600489 | 0.88 | KCNH2 (0.47) | KCNH2HPGDCYP3A4ALDH1A1TDP1 | |
| SCHEMBL15298988 | 0.84 | ALB (0.49) | KCNH2HPGDTDP1FTOGSTP1 | |
| SCHEMBL27087685 | 0.84 | KCNH2 (0.41) | KCNH2HPGDCYP3A4ALDH1A1TDP1 | |
| SCHEMBL29923531 | 0.84 | KCNH2 (0.41) | KCNH2HPGDCYP3A4ALDH1A1TDP1 | |
| SCHEMBL23599906 | 0.84 | FTO (0.51) | KCNH2HPGDCYP3A4TDP1FTO | |
| SCHEMBL23977365 | 0.83 | KCNH2 (0.40) | KCNH2HPGDCYP3A4ALDH1A1TDP1 | |
| SCHEMBL23509569 | 0.83 | KCNH2 (0.48) | KCNH2HPGDCYP3A4ALDH1A1TDP1 | |
| SCHEMBL16974360 | 0.82 | KCNH2 (0.43) | KCNH2HPGDCYP3A4ALDH1A1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2972227-B1 | DIGITALLY ENHANCED MICROSCOPY FOR MULTIPLEXED HISTOLOGY | VENTANA MED SYST INC (US) | 2020-05-06 | — | — | EP | disclosed |