Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 3/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 6/20 | 0.40 |
| ▸ | CDC25B | P30305 | 5/20 | 0.40 |
| ▸ | ACP1 | P24666 | 4/20 | 0.40 |
| ▸ | RECQL | P46063 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.40 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.40 |
| ▸ | HPSE | Q9Y251 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | FASN | P49327 | 1/20 | 0.32 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18940255 | 1.00 | MAOA (0.41) | MAOAPTPN1CDC25BACP1RECQL | |
| SCHEMBL21555847 | 0.89 | PTPN1 (0.40) | MAOAPTPN1CDC25BACP1RECQL | |
| SCHEMBL18919596 | 0.84 | PTPN1 (0.48) | PTPN1CDC25BACP1RECQLTDP1 | |
| SCHEMBL18919577 | 0.84 | PTPN1 (0.48) | PTPN1CDC25BACP1RECQLTDP1 | |
| SCHEMBL18919570 | 0.84 | PTPN1 (0.48) | PTPN1CDC25BACP1RECQLTDP1 | |
| SCHEMBL18919576 | 0.84 | PTPN1 (0.48) | PTPN1CDC25BACP1RECQLTDP1 | |
| SCHEMBL18919583 | 0.84 | PTPN1 (0.48) | PTPN1CDC25BACP1RECQLTDP1 | |
| SCHEMBL18919599 | 0.83 | PTPN1 (0.36) | PTPN1CDC25BACP1RECQLTDP1 | |
| SCHEMBL18919579 | 0.79 | PTPN1 (0.38) | PTPN1CDC25BACP1RECQLTDP1 | |
| SCHEMBL18940256 | 0.79 | MAOA (0.35) | MAOAPTPN1CDC25BACP1RECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10933048-B2 | Compounds and methods of treating bacterial infections | ULTUPHARMA AB (SE) | 2021-03-02 | — | — | US | disclosed |
| US-20200138777-A1 | COMPOUNDS AND METHODS OF TREATING BACTERIAL INFECTIONS | ULTUPHARMA AB (SE) | 2020-05-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10933048-B2 | Compounds and methods of treating bacterial infections | ELANE, TNF, NISCH | MAOA 216/4885PTPN1 3158/4885CDC25B 2547/4885 |
| US-20200138777-A1 | COMPOUNDS AND METHODS OF TREATING BACTERIAL INFECTIONS | ELANE, TNF, NISCH | MAOA 216/4885PTPN1 3158/4885CDC25B 2547/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.