Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 3/20 | 0.35 |
| ▸ | PTPN1 | P18031 | 6/20 | 0.34 |
| ▸ | CDC25B | P30305 | 4/20 | 0.34 |
| ▸ | ACP1 | P24666 | 3/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.34 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.34 |
| ▸ | HPSE | Q9Y251 | 1/20 | 0.34 |
| ▸ | PRKCA | P17252 | 6/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18919859 | 0.86 | CYP1A2 (0.41) | PTPN1CDC25BACP1MAPTRECQL | |
| SCHEMBL18940257 | 0.80 | PTPN1 (0.32) | PTPN1CDC25BACP1MAPTRECQL | |
| SCHEMBL21555849 | 0.79 | PRKCA (0.36) | PTPN1CDC25BACP1MAPTRECQL | |
| SCHEMBL21973203 | 0.79 | MAOA (0.41) | MAOAPTPN1CDC25BACP1MAPT | |
| SCHEMBL18940255 | 0.79 | MAOA (0.41) | MAOAPTPN1CDC25BACP1MAPT | |
| SCHEMBL21555847 | 0.69 | PTPN1 (0.40) | MAOAPTPN1CDC25BACP1MAPT | |
| SCHEMBL17356820 | 0.65 | PTPN1 (0.38) | MAOAPTPN1CDC25BACP1MAPT | |
| SCHEMBL18919596 | 0.65 | PTPN1 (0.48) | PTPN1CDC25BACP1MAPTRECQL | |
| SCHEMBL18919577 | 0.65 | PTPN1 (0.48) | PTPN1CDC25BACP1MAPTRECQL | |
| SCHEMBL18919583 | 0.65 | PTPN1 (0.48) | PTPN1CDC25BACP1MAPTRECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017095319-A1 | COMPOUNDS AND METHODS OF TREATING BACTERIAL INFECTIONS | ULTUPHARMA AB (SE) | 2017-06-08 | — | — | WO | disclosed |