Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1829308 | 0.74 | EPHX2 (0.45) | EPHX2HDAC6 | |
| SCHEMBL10202700 | 0.69 | EPHX2 (0.38) | EPHX2HDAC6 | |
| SCHEMBL3332193 | 0.69 | EPHX2 (0.38) | NOTUMEPHX2HDAC6 | |
| SCHEMBL18760057 | 0.67 | HDAC6 (0.47) | EPHX2HDAC6 | |
| SCHEMBL22990454 | 0.65 | — | — | |
| SCHEMBL9963212 | 0.64 | ALDH1A1 (0.36) | ALDH1A1EPHX2HDAC6 | |
| SCHEMBL31214294 | 0.64 | KDM4E (0.44) | NOTUMKDM4EALDH1A1EPHX2HDAC6 | |
| SCHEMBL18010984 | 0.64 | EPHX2 (0.35) | EPHX2HDAC6 | |
| SCHEMBL27259964 | 0.64 | — | — | |
| SCHEMBL12976224 | 0.64 | EPHX2 (0.38) | EPHX2HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3288936-B1 | BENZIMIDAZOLONE AND BENZOTHIAZOLONE COMPOUNDS AND THEIR USE AS AMPA RECEPTOR MODULATORS | JANSSEN PHARMACEUTICA NV (BE) | 2020-05-06 | — | — | EP | disclosed |