Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14562598 | 0.77 | EPHX2 (0.35) | EPHX2HDAC6 | |
| SCHEMBL1829308 | 0.74 | EPHX2 (0.45) | EPHX2HDAC6 | |
| SCHEMBL10202700 | 0.69 | EPHX2 (0.38) | EPHX2HDAC6 | |
| SCHEMBL18760057 | 0.67 | HDAC6 (0.47) | EPHX2HDAC6 | |
| SCHEMBL9963212 | 0.64 | ALDH1A1 (0.36) | EPHX2HDAC6 | |
| SCHEMBL21973442 | 0.64 | NOTUM (0.41) | EPHX2HDAC6 | |
| SCHEMBL31214294 | 0.64 | KDM4E (0.44) | EPHX2HDAC6 | |
| SCHEMBL3724843 | 0.64 | EPHX2 (0.38) | EPHX2HDAC6 | |
| SCHEMBL12976224 | 0.64 | EPHX2 (0.38) | EPHX2HDAC6 | |
| SCHEMBL2879549 | 0.64 | EPHX2 (0.38) | EPHX2HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10300067-B2 | Tetrahydropyridopyrimidine compound or salt thereof | TAIHO PHARMACEUTICAL CO., LTD. (JP) | 2019-05-28 | — | — | US | disclosed |
| EP-3150599-B1 | NOVEL TETRAHYDROPYRIDOPYRIMIDINE COMPOUND OR SALT THEREOF | TAIHO PHARMACEUTICAL CO LTD (JP) | 2018-10-24 | — | — | EP | disclosed |
| US-20180161331-A1 | NOVEL TETRAHYDROPYRIDOPYRIMIDINE COMPOUND OR SALT THEREOF | TAIHO PHARMACEUTICAL CO., LTD. (JP) | 2018-06-14 | — | — | US | disclosed |
| US-9889136-B2 | Tetrahydropyridopyrimidine compound or salt thereof | TAIHO PHARMACEUTICAL CO., LTD. (JP) | 2018-02-13 | — | — | US | disclosed |
| US-9662333-B2 | Tetrahydropyridopyrimidine compound or salt thereof | TAIHO PHARMACEUTICAL CO., LTD. (JP) | 2017-05-30 | — | — | US | disclosed |
| EP-3150599-A1 | NOVEL TETRAHYDROPYRIDOPYRIMIDINE COMPOUND OR SALT THEREOF | Taiho Pharmaceutical Co., Ltd. (JP) | 2017-04-05 | — | — | EP | disclosed |
| US-20160310496-A1 | NOVEL TETRAHYDROPYRIDOPYRIMIDINE COMPOUND OR SALT THEREOF | TAIHO PHARMACEUTICAL CO., LTD. (JP) | 2016-10-27 | — | — | US | disclosed |
| US-20160244444-A1 | NOVEL TETRAHYDROPYRIDOPYRIMIDINE COMPOUND OR SALT THEREOF | TAIHO PHARMACEUTICAL CO., LTD. (JP) | 2016-08-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180161331-A1 | NOVEL TETRAHYDROPYRIDOPYRIMIDINE COMPOUND OR SALT THEREOF | NR5A1, CYP17A1, AR | EPHX2 3227/4885HDAC6 240/4885 |
| US-10300067-B2 | Tetrahydropyridopyrimidine compound or salt thereof | NR5A1, CYP17A1, DPYD | EPHX2 2884/4885HDAC6 389/4885 |
| US-20160310496-A1 | NOVEL TETRAHYDROPYRIDOPYRIMIDINE COMPOUND OR SALT THEREOF | NR5A1, CYP17A1, AR | EPHX2 3227/4885HDAC6 240/4885 |
| US-20160244444-A1 | NOVEL TETRAHYDROPYRIDOPYRIMIDINE COMPOUND OR SALT THEREOF | AR, NR5A1, NR5A2 | EPHX2 3739/4885HDAC6 883/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.