Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.36 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | AR | P10275 | 1/20 | 0.33 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.32 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.32 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.32 |
| ▸ | PRKCQ | Q04759 | 2/20 | 0.31 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.31 |
| ▸ | CASP3 | P42574 | 1/20 | 0.31 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.31 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21973801 | 0.80 | PABPC1 (0.34) | DHODHALDH1A1MAPK1PABPC1 | |
| SCHEMBL21973794 | 0.79 | DHODH (0.37) | DHODHPABPC1AR | |
| SCHEMBL21973779 | 0.79 | TSHR (0.36) | ALDH1A1HSD17B10CYP1A2CYP3A4MAPK1 | |
| SCHEMBL21973705 | 0.75 | LRRK2 (0.39) | HSD17B10HPGDDGAT1ALOX15BRD4 | |
| SCHEMBL21974168 | 0.75 | PTGS2 (0.39) | PABPC1GAAHPGD | |
| SCHEMBL21973777 | 0.75 | PABPC1 (0.38) | ALDH1A1CYP1A2CYP3A4MAPK1CLK4 | |
| SCHEMBL21974156 | 0.75 | AR (0.40) | DHODHALDH1A1MAPK1KDM4EGAA | |
| SCHEMBL21974159 | 0.74 | DHODH (0.37) | DHODHALDH1A1PABPC1AR | |
| SCHEMBL21973782 | 0.73 | PABPC1 (0.39) | ALDH1A1MAPK1PABPC1HPGD | |
| SCHEMBL19392332 | 0.70 | KDM4E (0.42) | ALDH1A1MAPK1KDM4EGAAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3288936-B1 | BENZIMIDAZOLONE AND BENZOTHIAZOLONE COMPOUNDS AND THEIR USE AS AMPA RECEPTOR MODULATORS | JANSSEN PHARMACEUTICA NV (BE) | 2020-05-06 | — | — | EP | disclosed |