Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.91 |
| ▸ | CES2 | O00748 | 1/20 | 0.39 |
| ▸ | CES1 | P23141 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CA4 | P22748 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | EPHX1 | P07099 | 5/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.33 |
| ▸ | MGLL | Q99685 | 1/20 | 0.33 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11948880 | 1.00 | TSHR (0.91) | TSHRCES2CES1CA1CA2 | |
| SCHEMBL2193805 | 1.00 | TSHR (0.91) | TSHRCES2CES1CA1CA2 | |
| SCHEMBL811883 | 1.00 | TSHR (0.91) | TSHRCES2CES1CA1CA2 | |
| Cyclooctanol SCHEMBL8732936 | 1.00 | TSHR (0.91) | TSHRCES2CES1CA1CA2 | |
| SCHEMBL11948482 | 1.00 | TSHR (0.91) | TSHRCES2CES1CA1CA2 | |
| SCHEMBL23121456 | 1.00 | TSHR (0.91) | TSHRCES2CES1CA1CA2 | |
| Cyclooctanol SCHEMBL40903 | 1.00 | — | — | |
| Cyclohexanol SCHEMBL8503956 | 1.00 | TSHR (0.91) | TSHRCES2CES1CA1CA2 | |
| SCHEMBL653885 | 1.00 | TSHR (0.91) | TSHRCES2CES1CA1CA2 | |
| Cyclohexanol SCHEMBL5545 | 1.00 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1264594-B1 | Melanin production inhibitors and skincare products containing such inhibitors | TAKASAGO PERFUMERY CO LTD (JP) | 2006-11-29 | — | — | EP | claimed |
| US-6759557-B2 | MACROCYCLIC HYDROCARBON RINGS WITH HYDROXYL AND/OR KETONE FUNCTIONALITIES, SUCH AS CYCLOTETRADECANONE OR 2-HYDROXYCYCLOHEXADECANONE, OPTIONALLY WITH SKIN WHITENING AGENTS AND/OR UV ABSORBERS | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2004-07-06 | — | — | US | claimed |
| US-20030049213-A1 | Melanin production inhibitors and skincare products containing such inhibitors | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2003-03-13 | — | — | US | claimed |
| EP-1264594-A2 | Melanin production inhibitors and skincare products containing such inhibitors | Takasago International Corporation (JP) | 2002-12-11 | — | — | EP | claimed |
| US-20160000691-A1 | Topical Compositions And Methods For Whitening Skin | ELC MAN LLC (US) | 2016-01-07 | — | — | US | disclosed |
| US-20110171288-A1 | TOPICAL COMPOSITIONS AND METHODS FOR WHITENING SKIN | MOHAMMADI FATEMEH | 2011-07-14 | — | — | US | disclosed |
| EP-2254546-A2 | TOPICAL COMPOSITIONS AND METHODS FOR WHITENING SKIN | ELC Management LLC (US) | 2010-12-01 | — | — | EP | disclosed |
| WO-2009105294-A2 | TOPICAL COMPOSITIONS AND METHODS FOR WHITENING SKIN | ELC MANAGEMENT LLC (US) | 2009-08-27 | — | — | WO | disclosed |
| EP-1264594-B1 | Melanin production inhibitors and skincare products containing such inhibitors | TAKASAGO PERFUMERY CO LTD (JP) | 2006-11-29 | — | — | EP | disclosed |
| US-6759557-B2 | MACROCYCLIC HYDROCARBON RINGS WITH HYDROXYL AND/OR KETONE FUNCTIONALITIES, SUCH AS CYCLOTETRADECANONE OR 2-HYDROXYCYCLOHEXADECANONE, OPTIONALLY WITH SKIN WHITENING AGENTS AND/OR UV ABSORBERS | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2004-07-06 | — | — | US | disclosed |
| US-20030049213-A1 | Melanin production inhibitors and skincare products containing such inhibitors | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2003-03-13 | — | — | US | disclosed |
| EP-1264594-A2 | Melanin production inhibitors and skincare products containing such inhibitors | Takasago International Corporation (JP) | 2002-12-11 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160000691-A1 | Topical Compositions And Methods For Whitening Skin | CUTA, COL14A1, KRT18 | TSHR 4837/4885CES2 602/4885CES1 699/4885 |
| US-20030049213-A1 | Melanin production inhibitors and skincare products containing such inhibitors | TYR, AOC3, DOHH | TSHR 3284/4885CES2 1453/4885CES1 276/4885 |
| US-20110171288-A1 | TOPICAL COMPOSITIONS AND METHODS FOR WHITENING SKIN | CUTA, COL14A1, KRT18 | TSHR 4837/4885CES2 602/4885CES1 699/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.