SCHEMBL219742

SCHEMBL219742

Clc1ccc(N2CCNCC2)cc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ADRB1 P08588 7/20 1.00
HTR3E A5X5Y0 4/20 1.00
HTR3B O95264 4/20 1.00
HTR3A P46098 4/20 1.00
HTR3D Q70Z44 4/20 1.00
HTR3C Q8WXA8 4/20 1.00
SIGMAR1 Q99720 4/20 1.00
LTA4H P09960 2/20 0.79
CHRM2 P08172 1/20 0.63
CHRM4 P08173 1/20 0.63
CHRM1 P11229 1/20 0.63
CHRM3 P20309 1/20 0.63
CETP P11597 4/20 0.61
TP53 P04637 1/20 0.60
CYP1A2 P05177 1/20 0.60
CYP3A4 P08684 1/20 0.60
HTR1A P08908 1/20 0.60
CYP2D6 P10635 1/20 0.60
THRB P10828 1/20 0.60
CYP2C9 P11712 1/20 0.60

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL894618 1.00 ADRB1 (1.00) ADRB1HTR3EHTR3BHTR3AHTR3D
Hydrochloric Acid SCHEMBL708482 0.98 ADRB1 (0.96) ADRB1HTR3EHTR3BHTR3AHTR3D
Hydrochloric Acid SCHEMBL314621 0.98 ADRB1 (0.96) ADRB1HTR3EHTR3BHTR3AHTR3D
SCHEMBL7527162 0.94 ADRB1 (0.88) ADRB1HTR3EHTR3BHTR3AHTR3D
Formaldehyde SCHEMBL27861281 0.92 ADRB1 (0.85) ADRB1HTR3EHTR3BHTR3AHTR3D
Phenylpiperazine SCHEMBL29089117 0.92 ADRB1 (0.85) ADRB1HTR3EHTR3BHTR3AHTR3D
SCHEMBL658716 0.92 ADRB1 (0.85) ADRB1HTR3EHTR3BHTR3AHTR3D
Bicarbonate SCHEMBL11625611 0.90 ADRB1 (0.81) ADRB1HTR3EHTR3BHTR3AHTR3D
SCHEMBL588594 0.89 ADRB1 (0.79) ADRB1HTR3EHTR3BHTR3AHTR3D
Alcohol SCHEMBL11585083 0.89 ADRB1 (0.79) ADRB1HTR3EHTR3BHTR3AHTR3D

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 2652 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4687967-A1 MENINGOCOCCAL PROTEIN BASED VACCINE FORMULATIONS AND METHODS FORMANUFACTURING THEREOF Serum Institute Of India Private Limited (IN) 2026-02-11 EP claimed
US-12510460-B2 Method and apparatus for analyzing flow matrix data, and computer device Hangzhou ShineDo Biotech. Co.Ltd. (CN) 2025-12-30 US claimed
US-12486401-B2 ‘Smart’ hydrogel for the radiosensitization and sustained delivery of therapeutics triggered by irradiation THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) 2025-12-02 US claimed
EP-4602057-A1 ENGINEERED FLAVIVIRUS ENVELOPE GLYCOPROTEIN IMMUNOGENIC COMPOSITIONS AND METHODS OF USE University of Maryland, Baltimore (US) 2025-08-20 EP claimed
CN-120037890-A Potato starch beta-cyclodextrin composite nano sponge and preparation method and application thereof 广东科沃德新材料科技有限公司 2025-05-27 CN claimed
WO-2024231957-A1 2'-{HETEROCYCLYL (ARYL/ALKYL) METHYL}-CANNABIDIOL COMPOUNDS AND PROCESS FOR PREPARATION THEREOF COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH AN INDIAN REGISTERED BODY INCORPORATED UNDER THE REGN. OF SOC. ACT (ACT XXI OF 1860) (IN) 2024-11-14 WO claimed
WO-2024211384-A1 EGG BASED MICROCARRIERS AND SCAFFOLDS FOR CELLULAR AGRICULTURE AND OTHER APPLICATIONS HATCHLESS INC. (US) 2024-10-10 WO claimed
WO-2024201502-A1 MENINGOCOCCAL PROTEIN BASED VACCINE FORMULATIONS AND METHODS FOR MANUFACTURING THEREOF SERUM INSTITUTE OF INDIA PRIVATE LIMITED (IN) 2024-10-03 WO claimed
CN-117050204-B Penthorn grass polysaccharide PCPP and application thereof 四川农业大学 2024-07-02 CN claimed
EP-4386359-A1 METHOD FOR ANALYZING FLOW MATRIX DATA, AND COMPUTER DEVICE Hangzhou ShineDo Biotech. Co.Ltd. (CN) 2024-06-19 EP claimed
WO-1991012263-A1 SYMMETRICAL BIPEPTIDES INCLUDING A POLYALKYLENE-GYLCOL GROUP, METHOD OF PREPARATION AND USE IN PROTEASE DETERMINATION SERBIO (FR) 1991-08-22 WO claimed
EP-0434341-A1 Diazine derivatives ZENECA LIMITED (GB) 1991-06-26 EP claimed
US-4960900-A ANTICONVULSANTS Institut de Ercherches Chimiques et Biologiques Appliquees (I.R.C.E.B.A.) (FR) 1990-10-02 US claimed
US-4925841-A ANTICONVULSANTS TEMPLE UNIVERSITY OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) 1990-05-15 US claimed
EP-0322296-A1 Oximino-thiazole derivatives, their preparation and their therapeutical use INSTITUT DE RECHERCHES CHIMIQUES ET BIOLOGIQUES APPLIQUEES (I.R.C.E.B.A.) Société à responsabilité limitée dite: (FR) 1989-06-28 EP claimed
EP-0174242-B1 1-(AMINO-PHENYL)-2-AMINO PROPANON DERIVATIVES, THEIR USE IN THERAPY AND PROCESS FOR THEIR PREPARATION LABORATOIRE L. LAFON Société anonyme dite: (FR) 1988-01-13 EP claimed
EP-0138714-B1 1-(ACETYLAMINOPHENYL)-2-AMINO-PROPANONE DERIVATIVES, THEIR THERAPEUTICAL USE AND PROCESS FOR THEIR PREPARATION LABORATOIRE L. LAFON Société anonyme dite: (FR) 1987-05-20 EP claimed
EP-0174242-A2 1-(Amino-phenyl)-2-amino propanon derivatives, their use in therapy and process for their preparation LABORATOIRE L. LAFON Société anonyme dite: (FR) 1986-03-12 EP claimed
EP-0138714-A2 1-(Acetylaminophenyl)-2-amino-propanone derivatives, their therapeutical use and process for their preparation LABORATOIRE L. LAFON Société anonyme dite: (FR) 1985-04-24 EP claimed
US-3959281-A CORONARY DILATORS CASSELLA FARBWERKE MAINKUR AKTIENGESELLSCHAFT (DT) 1976-05-25 US claimed