Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NNMT | P40261 | 2/20 | 0.34 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.32 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22930894 | 0.75 | GRM4 (0.32) | GRM4 | |
| SCHEMBL29541013 | 0.70 | PRKCI (0.47) | GRM4 | |
| SCHEMBL25789867 | 0.69 | NNMT (0.45) | NNMTCREBBP | |
| SCHEMBL21975058 | 0.65 | GRIA2 (0.30) | — | |
| SCHEMBL25425626 | 0.62 | NNMT (0.47) | NNMT | |
| SCHEMBL25425630 | 0.62 | NNMT (0.47) | NNMT | |
| SCHEMBL31600600 | 0.62 | NNMT (0.41) | NNMT | |
| SCHEMBL18599971 | 0.60 | MAPKAPK2 (0.34) | — | |
| SCHEMBL13507512 | 0.60 | NNMT (0.42) | NNMT | |
| SCHEMBL24126980 | 0.60 | NNMT (0.39) | NNMT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2343298-B9 | Heteroaryl substituted pyrrolo[2,3-b]pyridines and pyrrolo[2,3-b]pyrimidines as Janus kinase inhibitors | INCYTE HOLDINGS CORP (US) | 2020-05-06 | — | — | EP | disclosed |