Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM4 | Q14833 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19062318 | 0.84 | GRM2 (0.32) | — | |
| SCHEMBL21974558 | 0.75 | NNMT (0.34) | GRM4 | |
| SCHEMBL29541013 | 0.71 | PRKCI (0.47) | GRM4 | |
| SCHEMBL15072215 | 0.63 | ROCK1 (0.34) | GRM4 | |
| SCHEMBL15072224 | 0.61 | CYP2A6 (0.32) | — | |
| SCHEMBL24422192 | 0.59 | — | — | |
| SCHEMBL13833543 | 0.58 | HTR2C (0.32) | — | |
| SCHEMBL7505476 | 0.57 | NCF1 (0.32) | — | |
| SCHEMBL98273 | 0.56 | AURKB (0.56) | GRM4 | |
| SCHEMBL29540441 | 0.56 | AURKB (0.56) | GRM4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3838903-B1 | PYRROLO[2,3-D]PYRIMIDINE DERIVATIVE AS JANUS KINASE INHIBITOR | INCYTE HOLDINGS CORP (US) | 2023-11-22 | — | — | EP | disclosed |
| EP-3466953-B1 | PYRROLO[2,3-D]PYRIMIDINE DERIVATIVE AS JANUS KINASE INHIBITOR | INCYTE HOLDINGS CORP (US) | 2021-02-03 | — | — | EP | disclosed |