Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4D | Q08499 | 4/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA7 | P43166 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8784515 | 0.82 | PDE4D (0.56) | PDE4DKMT2APDE4BMAPK1USP2 | |
| SCHEMBL21974827 | 0.81 | KDM4E (0.42) | PDE4DKMT2AUSP2KDM4EALDH1A1 | |
| SCHEMBL1357734 | 0.81 | KMT2A (0.40) | PDE4DKMT2AUSP2KDM4EALDH1A1 | |
| SCHEMBL26104148 | 0.81 | PDE4D (0.48) | PDE4DKMT2APDE4BMAPK1USP2 | |
| SCHEMBL10577895 | 0.79 | MAPK1 (0.56) | PDE4DKMT2APDE4BMAPK1USP2 | |
| SCHEMBL2963689 | 0.79 | L3MBTL1 (0.53) | PDE4DKMT2APDE4BMAPK1USP2 | |
| SCHEMBL20427919 | 0.79 | PDE4D (0.43) | PDE4DKMT2APDE4BMAPK1USP2 | |
| SCHEMBL16937220 | 0.79 | KDM4E (0.40) | PDE4DKMT2APDE4BMAPK1USP2 | |
| SCHEMBL23123432 | 0.78 | KMT2A (0.46) | PDE4DKMT2APDE4BMAPK1USP2 | |
| SCHEMBL10362229 | 0.78 | PDE4D (0.46) | PDE4DKMT2APDE4BMAPK1USP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112174891-B | Preparation method of penflufen metabolite | 浙江省农业科学院 | 2022-02-01 | — | — | CN | disclosed |
| CN-112174891-A | Preparation method of penflufen metabolite | 浙江省农业科学院 | 2021-01-05 | — | — | CN | disclosed |
| EP-3650443-A1 | CONTINUOUS FLOW SYNTHESIS OF FLUORINATED OR NON-FLUORINATED PYRAZOLES | Fujian Yongjing Technology Co., Ltd. (CN) | 2020-05-13 | — | — | EP | disclosed |
| US-20200140390-A1 | Process for the Manufacture of Pyrazoles or Pyrimidones | FUJIAN YONGJING TECHNOLOGY CO., LTD. (CN) | 2020-05-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200140390-A1 | Process for the Manufacture of Pyrazoles or Pyrimidones | DHFR, CYP4X1, CYP2F1 | PDE4D 416/4885KMT2A 733/4885PDE4B 513/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.