Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR5 | Q9H228 | 2/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | S1PR1 | P21453 | 13/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.33 |
| ▸ | RORC | P51449 | 4/20 | 0.32 |
| ▸ | GSK3B | P49841 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25857139 | 0.68 | CDK2 (0.47) | S1PR5KCNH2S1PR1CYP2C9RORC | |
| SCHEMBL1293371 | 0.63 | S1PR1 (0.54) | S1PR1KDM4ENPC1ALDH1A1MAPT | |
| SCHEMBL25856942 | 0.63 | S1PR1 (0.34) | S1PR1CYP2C9RORC | |
| SCHEMBL1293378 | 0.62 | S1PR1 (0.55) | S1PR1S1PR3RORC | |
| SCHEMBL25856764 | 0.62 | PGR (0.41) | S1PR1 | |
| SCHEMBL20178542 | 0.61 | CYP1A2 (0.37) | S1PR1RORCNPC1ALDH1A1RAB9A | |
| SCHEMBL21890666 | 0.61 | S1PR1 (0.57) | S1PR5KCNH2S1PR1S1PR3 | |
| SCHEMBL23558399 | 0.60 | CTSC (0.35) | S1PR1NPC1ALDH1A1MAPTRAB9A | |
| SCHEMBL2413739 | 0.60 | XDH (0.46) | S1PR1RORC | |
| SCHEMBL19507973 | 0.60 | S1PR1 (0.54) | S1PR1S1PR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3647309-A1 | AMINO ALCOHOL DERIVATIVE, PHARMACEUTICAL COMPOSITION AND APPLICATION THEREOF | Beijing Foreland Pharma Co., Ltd. (CN) | 2020-05-06 | — | — | EP | disclosed |